Author

A. Taggart

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Assay:clinical cohort / trial· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Palmarini· 3 shared Q. Gu· 3 shared W. Furnon· 3 shared C. Boutell· 2 shared M. Stewart· 2 shared M. Varela· 2 shared M. Varjak· 2 shared O. MacLean· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

M. Palmarini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection

V. Herder, M. Caporale, O. MacLean, D. Pintus, X. Huang, K. Nomikou, N. Palmalux, J. Nichols, R. Scivoli, C. Boutell, A. Taggart, J. Allan, H. Malik, G. Ilia, Q. Gu, , M. Palmarini

This study uses machine learning to identify key viral and host processes associated with varying severity in bluetongue virus infection in sheep.

bioRxiv · Feb 23, 2024 · PreprintMicrobiology

Timing and magnitude of the type-I interferon response are determinants of disease tolerance in arbovirus infection

A. Hardy, S. Bakshi, W. Furnon, O. MacLean, Q. Gu, M. Varjak, M. Varela, M. A. Aziz, A. Shaw, R. M. Pinto, N. C. Ruiz, C. Mullan, A. Taggart, A. Filipe, R. E. Randall, , M. Palmarini

This study shows that the timing and magnitude of the type-I interferon response determine disease tolerance in bluetongue virus infection between sheep and cattle.

bioRxiv · Oct 19, 2022 · PreprintMicrobiology

Zoonotic avian influenza viruses evade human BTN3A3 restriction

R. M. Pinto, S. Bakshi, S. Lytras, M. K. Zakaria, S. Swingler, J. C. Worrell, V. Herder, M. Varjak, N. Cameron-Ruiz, M. Collados-Rodriguez, M. Varela, A. Wickenhagen, C. Loney, Y. Pei, J. Hughes, , M. Palmarini

This study identifies BTN3A3 as a human restriction factor that inhibits avian influenza viruses but not human IAVs, with resistance linked to specific NP mutations.

bioRxiv · Jun 14, 2022 · PreprintMicrobiology

COVID-19: A need for new rather than repurposed antiviral drugs.

D. Kovacs, C. Davis, P. Cannon, M. McFarlane, S. M. Rainey, R. Pinto, M. E. Stewart, A. M. Szemiel, A. Taggart, A. Kohl, F. Marra, E. C. Thomson, J. T. Scott

This paper reviews 29 FDA-approved antiviral compounds for COVID-19 treatment, finds limited clinical efficacy of repurposed drugs, and highlights the need for novel antivirals.

bioRxiv · Mar 25, 2021 · PreprintMicrobiology