N. Petrovsky

A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

This study shows that a vaccine targeting the L9 epitope of CSP in Plasmodium falciparum provides protection against blood-stage malaria in mice.

Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

This study develops a recombinant SARS-CoV-2 spike protein vaccine, Covax-19, formulated with Advax-SM adjuvant, showing protection against COVID-19 in mice and ferrets.

Combination adjuvants enhance recombinant protein vaccine protection against fungal infection

This study shows that combining adjuvants with a fungal recombinant protein vaccine enhances protection against Blastomyces dermatitidis infection by inducing specific T cell responses.

Accelerated vaccine induction of IgM neutralising antibody enables same day vaccine protection against a lethal influenza virus challenge

This study shows that a novel adjuvant can enable same-day protection against a lethal influenza virus challenge through IgM neutralizing antibodies.

Advax adjuvant formulations promote protective immunity against aerosol Mycobacterium tuberculosis in the absence of deleterious inflammation and reactogenicity

This study evaluates Advax adjuvant formulations for tuberculosis vaccine efficacy, showing they provide strong protection without causing inflammation or reactogenicity.

An Epitope-based Malaria Vaccine Targeting the Junctional Domain of Circumsporozoite Protein

This paper develops a malaria vaccine targeting the CIS43 epitope on CSP using Qβ VLPs, showing high immunogenicity and partial protection in mice and macaques.

Mucosal delivery of a multistage subunit vaccine promotes development of lung-resident memory T cells and affords interleukin-17-dependant protection against pulmonary tuberculosis

This paper shows that a mucosal vaccine induces lung-resident memory T cells expressing IL-17, which protect against tuberculosis, and that IL-17 is critical for this protection.