R. Raman

Genome-wide association study elucidates the genetic architecture of manganese tolerance in Brassica napus

This study identifies genetic loci and genes involved in manganese tolerance in canola using genome-wide association analysis and functional assays.

2.5D Actuating Substrates Enable Decoupling the Mechanical and Biochemical Effects of Muscle Exercise on Motor Neurons

This study uses 2.5D actuating substrates to show that both mechanical and biochemical effects of muscle exercise significantly influence motor neuron growth and maturation.

The ultrastructure of the starfish skeleton is correlated with mechanical stress

This study investigates the relationship between mechanical stress and ultrastructure in the endoskeleton of Asterias rubens, finding that adaptation to mechanical loads is common in Deuterostomia but material remodeling is specific to vertebrates.

Machine Learning-Guided Antibody Engineering That Leverages Domain Knowledge To Overcome The Small Data Problem

This paper presents a machine learning platform that enhances antibody affinity and neutralizing potency using domain knowledge and limited experimental data.

A structural dynamic explanation for observed escape of SARS-CoV-2 BA.2 variant mutation S371L/F

The paper explains the broad immune escape of SARS-CoV-2 BA.2 variant mutations S371L/F through structural analysis of spike trimer conformational dynamics.

Multi-environment QTL analysis delineates a major locus associated with homoeologous exchanges for water-use efficiency and seed yield in allopolyploid Brassica napus

This study identifies a major QTL on chromosome A09 associated with water-use efficiency and seed yield in Brassica napus, linked to homoeologous exchanges and gene expression differences.

Mapping Potential Antigenic Drift Sites (PADS) on SARS-CoV-2 Spike in Continuous Epitope-Paratope Space

The paper identifies potential antigenic drift sites on SARS-CoV-2 spike protein and projects them into epitope-paratope space to assess mutation synergy across variants of concern.

QTL mapping reveals genomic regions for yield based on incremental tolerance index to drought stress and related agronomic traits in canola

This study identifies genomic regions associated with drought tolerance and yield in canola using QTL mapping, with markers that could improve breeding for drought resilience.

GWAS hints at pleiotropic roles for FLOWERING LOCUS T in flowering time and yield-related traits in canola

The paper identifies genetic associations and expression patterns of FT paralogs in canola, linking them to flowering time and yield-related traits through GWAS and QTL analyses.