Author

R. S. Bon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

D. J. Beech· 2 shared A. Balgi· 1 shared A. Baradaran-Heravi· 1 shared A. Droop· 1 shared A. J. Davies· 1 shared A. Patel· 1 shared A. V. Zholos· 1 shared B. Da Silva· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. J. Beech

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pico145 inhibits TRPC4-mediated mICAT and postprandial small intestinal motility

D. O. Dryn, M. I. Melnyk, R. S. Bon, D. J. Beech, A. V. Zholos

This study shows that Pico145 inhibits TRPC4-mediated mICAT and reduces postprandial intestinal motility in mice.

bioRxiv · Aug 7, 2023 · PreprintPharmacology & Toxicology

Suppression of aminoglycoside-induced premature termination codon readthrough by the TRP channel inhibitor AC1903

A. Baradaran-Heravi, C. C. Bauer, I. B. Pickles, S. Hosseini-Farahabadi, A. Balgi, K. Choi, D. M. Linley, D. J. Beech, M. Roberge, R. S. Bon

This study shows that AC1903 suppresses aminoglycoside-induced PTC readthrough by inhibiting multiple TRPC channels, but its mechanism remains unclear.

bioRxiv · Apr 7, 2021 · PreprintPharmacology & Toxicology

Need for speed: Examining protein behaviour during cryoEM grid preparation at different timescales

D. P. Klebl, M. S. C. Gravett, D. Kontziampasis, D. J. Wright, R. S. Bon, D. Monteiro, M. Trebbin, F. Sobott, H. D. White, M. Darrow, R. F. Thompson, s. P. muench

This study examines how different macromolecular complexes behave during cryoEM grid preparation at various timescales using three vitrification devices.

bioRxiv · May 14, 2020Biochemistry

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

E. S. Polson, V. B. Kuchler, C. Abbosh, E. M. Ross, R. K. Mathew, H. A. Beard, E. Chuntharpursat-Bon, J. Williams, B. Da Silva, H. Shao, A. Patel, A. J. Davies, A. Droop, H. B. S. Griffiths, P. Chumas, , H. Wurdak

The paper shows KHS101 inhibits HSPD1 in glioblastoma cells, causing metabolic dysfunction and tumor growth reduction without affecting normal cells.

bioRxiv · Oct 18, 2017Cancer Biology