Author

R. S. E. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:metabolomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

S. J. Blanksby· 4 shared A. P. Bowman· 2 shared B. L. J. Poad· 2 shared C. C. Nelson· 2 shared D. L. Marshall· 2 shared K. D. Tousignant· 2 shared S. R. Ellis· 2 shared A. H. Benfield· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCancer Biology

S. J. Blanksby

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A High-Throughput Data-Independent Acquisition Workflow for Deep Characterisation of the sn-Isomer Lipidome

J. A. Michael, R. S. E. Young, R. Balez, L. J. Jekimovs, D. L. Marshall, B. L. J. Poad, T. W. Mitchell, S. J. Blanksby, C. S. Ejsing, S. R. Ellis

The paper introduces a high-throughput workflow for characterizing sn-isomer lipidomes, identifying more sn-isomer pairs and revealing differences between cell lines.

bioRxiv · Nov 4, 2023 · PreprintCell Biology

Membrane-active peptides escape drug-resistance in cancer

A. H. Benfield, F. Vernen, R. S. E. Young, F. N. Bufi, H. Hammerlindl, D. J. Craik, H. Schaider, N. Lawrence, S. J. Blanksby, S. T. Henriques

This study shows membrane-active peptides can kill drug-resistant melanoma cells without inducing resistance, suggesting their potential as therapeutic agents.

bioRxiv · Oct 27, 2022 · PreprintCancer Biology

Isomeric lipid signatures reveal compartmentalised fatty acid metabolism in cancer

R. S. E. Young, A. P. Bowman, K. D. Tousignant, B. L. J. Poad, J. H. Gunter, L. K. Philp, C. C. Nelson, S. Ellis, R. M. A. Heeren, M. C. Sadowski, S. J. Blanksby

This study uses stable-isotope labelled fatty acids to reveal distinct metabolic fates of exogenous and de novo synthesized fatty acids in cancer cells, showing compartmentalized lipid metabolism.

bioRxiv · Nov 1, 2021 · PreprintCancer Biology

Metabolic plasticity in cancer activates apocryphal pathways for lipid desaturation

R. S. E. Young, A. P. Bowman, E. D. Williams, K. D. Tousignant, C. L. Bidgood, V. R. Narreddula, R. Gupta, D. L. Marshall, B. L. Poad, C. C. Nelson, S. R. Ellis, R. M. Heeren, M. Sadowski, S. J. Blanksby

The paper reveals metabolic plasticity in cancer through isomer-resolved lipidomics, identifying apocryphal pathways for lipid desaturation and their impact on lipid structure and function.

bioRxiv · Jun 7, 2020 · PreprintBiochemistry