Author

C. W. Wasson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

F. Del Galdo· 4 shared R. L. Ross· 3 shared A. Macdonald· 2 shared A. Samson· 2 shared B. Caballero-Ruiz· 2 shared D. Evans· 2 shared E. De Lorenzis· 2 shared E. L. Morgan· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

F. Del Galdo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Chloride intracellular channel 4 (CLIC4) is a global regulator of type 1 interferon signaling in Systemic Sclerosis (SSc) epithelial cells

C. W. Wasson, S. L. Dibb, B. Caballero Ruiz, E. M. Clavane, R. Wells, V. Kakkar, E. De Lorenzis, R. L. Ross, J. Bryon, E. Derrett-Smith, C. P. Denton, P. J. Meakin, F. Del Galdo

This study shows CLIC4 regulates type 1 interferon signaling in SSc epithelial cells and inhibiting it blocks IFN pathway activation.

bioRxiv · Mar 8, 2024 · PreprintImmunology

E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer

M. R. Patterson, A. S. Meijers, E. L. Ryder, J. A. Scarth, D. Evans, A. L. Turner, C. W. Wasson, J. E. Darell, C. D. James, M. Wang, J. E. Ladbury, I. M. Morgan, A. Samson, E. L. Morgan, A. Macdonald

This study shows that HPV E7 represses miR-203, leading to LASP1 upregulation and promoting proliferation in HPV-positive cervical cancer.

bioRxiv · Jan 8, 2024Cancer Biology

Systemic Sclerosis dermal fibroblast exosomes trigger a Type 1 interferon response in keratinocytes through the TBK/JAK/STAT signalling axis

J. Bryon, C. W. Wasson, K. Koeppen, F. Chandler, L. F. Willis, E. Klein, E. Zeqiraj, R. L. Ross, F. Del Galdo

bioRxiv · Dec 14, 2023Immunology

The Beta secretase BACE1 drives fibroblasts activation in Systemic Sclerosis through the APP/Beta-catenin/Notch signalling axis

C. W. Wasson, E. De Lorenzis, E. M. Clavane, R. L. Ross, K. A. Walker, B. Caballero-Ruiz, C. Antinozzi, R. Wells, G. Migneco, J. M. Y. Brown, N. A. Riobo-Del Galdo, L. Di Luigi, C. S. McKimmie, F. Del Galdo, P. J. Meakin

This study shows BACE1 drives fibroblast activation in systemic sclerosis via the APP/Beta-catenin/Notch axis and identifies BACE1 as a potential therapeutic target.

bioRxiv · Dec 22, 2022Immunology

Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

J. A. Scarth, C. W. Wasson, M. R. Patterson, D. Evans, D. Barba-Moreno, H. Carden, A. Whitehouse, J. Mankouri, A. Samson, E. L. Morgan, A. Macdonald

This study shows that HPV exploits KATP channels to promote cervical cancer cell proliferation through MAPK/AP-1 signaling.

bioRxiv · Sep 22, 2022Microbiology

Chloride intracellular channel 4 (CLIC4) expression is transcriptionally regulated by crosstalk of the TGF-beta, Wnt and Hedgehog signalling pathways

C. W. Wasson, B. Caballero-Ruiz, J. Mankouri, G. Canettieri, N. A. Riobo-Del Galdo, F. Del Galdo

This study identifies that TGF-beta, Wnt, and Hedgehog signaling pathways cooperatively regulate CLIC4 expression in fibroblasts, with implications for fibrosis.

bioRxiv · Jun 29, 2021 · PreprintCell Biology