Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis
Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes, Reuben N. Scott, Ana Cardus Figueras, Sandra Dimonte, Daniela O. Costa, Ngoc‐Nga Vinh, Federica Monaco, Robert L. Jenkins, Xiao Liu, Myles Lewis, Jason P. Twohig, Carol Guy, Aisling S. Morrin, , Simon A. Jones
The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.
bioRxiv · Nov 1, 2025 · PreprintPathology