Author

Brendan John Jenkins

The University of AdelaideORCID 0000-0002-7552-4656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Aisling S. Morrin· 2 shared Alicia Derrac SoriaiD· 2 shared Ana Cardus FiguerasiD· 2 shared Barbara SzomolayiD· 2 shared Benjamin C. CossinsiD· 2 shared Carol GuyiD· 2 shared Costantino PitzalisiD· 2 shared Ernest H ChoyiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Aisling S. Morrin

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2 papers

Recent·Most cited

Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis

Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes, Reuben N. Scott, Ana Cardus Figueras, Sandra Dimonte, Daniela O. Costa, Ngoc‐Nga Vinh, Federica Monaco, Robert L. Jenkins, Xiao Liu, Myles Lewis, Jason P. Twohig, Carol Guy, Aisling S. Morrin, , Simon A. Jones

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

bioRxiv · Nov 1, 2025 · PreprintPathology

IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.

Alicia Derrac Soria, Myles Lewis, Xiao Liu, Jason P. Twohig, Federica Monaco, Sandra Dimonte, Ana Cardus Figueras, Aisling S. Morrin, Carol Guy, Benjamin C. Cossins, Robert A. Benson, Robert Andrews, Barbara Szomolay, Ernest H Choy, Paul Garside, , Simon A. Jones

The paper identifies CRTAM-expressing CD4+ T-cells in lymphoid-driven synovitis and shows that IL-6 and IL-27 inhibit their activation through STAT3 and ZEB1.

bioRxiv · Sep 3, 2024 · PreprintImmunology