Author

David Gregory Hill

University of BristolORCID 0000-0001-5993-6194Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Aisling S. Morrin· 3 shared Gareth Wyn JonesiD· 3 shared Simon A. JonesiD· 3 shared Ana Cardus FiguerasiD· 2 shared Carol GuyiD· 2 shared Daniela O. CostaiD· 2 shared Ernest ChoyiD· 2 shared Federica Monaco· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Aisling S. Morrin

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 17, 2026

Inflammatory arthritis disrupts ocular immune privilege by compromising blood-retinal barrier integrity and promoting uveitogenic T cell recruitment

Simon Eastham, Amy Ward, Chloe Moscrop…·Gareth Wyn Jones

This study shows inflammatory arthritis disrupts the blood-retinal barrier and promotes T cell recruitment to the eye, increasing susceptibility to uveitis without causing overt ocular disease.

DOI 10.64898/2026.07.13.738174

mouseexperimental assay

𝕏 PostBluesky

PathologybioRxivPreprintNov 1, 2025

Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis

Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes…·Simon A. Jones

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

DOI 10.1101/2025.11.01.686006

mousebulk RNA-seq

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintMar 26, 2025

Interleukin-6 elevates thrombosis via pro-coagulant phospholipids from platelet 12-lipoxygenase in rheumatoid arthritis.

Daniela O. Costa, Stuart T.O Hughes, Robert L. Jenkins…·Valerie B. O’Donnell

This study identifies IL-6's role in elevating thrombosis in RA via platelet 12-lipoxygenase-generated pro-coagulant phospholipids.

3 citations

mousehuman

𝕏 PostBluesky