Author

Sandra Dimonte

Cardiff UniversityORCID 0000-0002-4612-4979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aisling S. Morrin· 3 shared Gareth Wyn JonesiD· 3 shared Robert AndrewsiD· 3 shared Simon A. JonesiD· 3 shared Alicia Derrac SoriaiD· 2 shared Ana Cardus FiguerasiD· 2 shared Barbara SzomolayiD· 2 shared Benjamin C. CossinsiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

Aisling S. Morrin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inflammatory arthritis disrupts ocular immune privilege by compromising blood-retinal barrier integrity and promoting uveitogenic T cell recruitment

Simon Eastham, Amy Ward, Chloe Moscrop, David Gregory Hill, Aisling S. Morrin, Sandra Dimonte, Alison Young, Simon A. Jones, Jian Liu, Andrew D. Dick, David A. Copland, Lindsay B. Nicholson, Gareth Wyn Jones

This study shows inflammatory arthritis disrupts the blood-retinal barrier and promotes T cell recruitment to the eye, increasing susceptibility to uveitis without causing overt ocular disease.

bioRxiv · Jul 17, 2026 · PreprintImmunology

Comprehensive lipidomics of tissue macrophages reveal LTE4-driven eosinophil survival

Magdalena A. Czubala, Patricia Rodrigues, Natacha Ipseiz, Marcela Rosas, Sandra Dimonte, Iestyn Pope, Christine Hinz, Dina Fathalla, Jorge Álvarez-Jarreta, Victoria J. Tyrrell, Wolfgang Langbein, Paola Borri, Robert Andrews, Valerie B. O’Donnell, Philip R. Taylor

The paper identifies GATA6's role in regulating sphingolipid and CysLT metabolism in peritoneal macrophages, leading to eosinophil survival via CysLT signaling.

bioRxiv · Jun 16, 2026 · PreprintImmunology

Discrete cytokine signaling networks instruct distinctsynovial pathotypes in inflammatory arthritis

Alicia Derrac Soria, David Gregory Hill, Stuart T. O. Hughes, Reuben N. Scott, Ana Cardus Figueras, Sandra Dimonte, Daniela O. Costa, Ngoc‐Nga Vinh, Federica Monaco, Robert L. Jenkins, Xiao Liu, Myles Lewis, Jason P. Twohig, Carol Guy, Aisling S. Morrin, , Simon A. Jones

The paper identifies distinct cytokine signaling networks in mouse models of arthritis that mirror human RA synovial pathotypes, revealing molecular mechanisms underlying disease heterogeneity.

bioRxiv · Nov 1, 2025 · PreprintPathology

IL-6 and IL-27 negatively regulate CRTAM-expressing CD4+ T-cells associated with lymphoid-driven synovitis.

Alicia Derrac Soria, Myles Lewis, Xiao Liu, Jason P. Twohig, Federica Monaco, Sandra Dimonte, Ana Cardus Figueras, Aisling S. Morrin, Carol Guy, Benjamin C. Cossins, Robert A. Benson, Robert Andrews, Barbara Szomolay, Ernest H Choy, Paul Garside, , Simon A. Jones

The paper identifies CRTAM-expressing CD4+ T-cells in lymphoid-driven synovitis and shows that IL-6 and IL-27 inhibit their activation through STAT3 and ZEB1.

bioRxiv · Sep 3, 2024 · PreprintImmunology