Author

Riley Luebbers

Saint Louis University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Poonam RoshaniD· 2 shared Sofia S. OrigantiiD· 2 shared Abhinav VayyetiiD· 1 shared Aidan Antony· 1 shared Aparna Biswas· 1 shared Ayush MistryiD· 1 shared Edwin AntonyiD· 1 shared Frank A. TedeschiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Poonam RoshanORCID

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Author profile →

2 papers

Recent·Most cited

Mechanism of RPA phosphocode priming and tuning by Cdk1/Wee1 signaling circuit

Poonam Roshan, Vikas Kaushik, Ayush Mistry, Abhinav Vayyeti, Aidan Antony, Riley Luebbers, Jaigeeth Deveryshetty, Edwin Antony, Sofia S. Origanti

This study identifies a feedback mechanism involving Cdk1/Wee1 signaling that primes and tunes RPA phosphorylation, crucial for cell cycle progression and DNA damage response.

Nature Communications · Dec 9, 2025Peer-reviewedBiochemistry

Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression.

Poonam Roshan, Aparna Biswas, Stella Anagnos, Riley Luebbers, Kavya Meena Harish, Sinthyia Ahmed, Megan Li, Nicholas V. Nguyen, Gao Zhou, Frank A. Tedeschi, Vivian M. Hathuc, Zhenguo Lin, Zachary Adam Hamilton, Sofia S. Origanti

This study shows that eIF6 modulates ribosomal subunit associations, affecting mitotic exit and cancer progression by altering translation efficiency of mitotic factors.

bioRxiv · Jun 24, 2024 · PreprintMolecular Biology