Author

Rohan K. Goyal

UPMC Hillman Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Aina E. CoheniD· 1 shared Alexander DeitersiD· 1 shared Brisa Caroline Alves ChagasiD· 1 shared Daniel Calero· 1 shared Dennis P. StegmanniD· 1 shared Guillermo A. CaleroiD· 1 shared Guowu LiniD· 1 shared Igor V. KurnikoviD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aina E. CohenORCID

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1 paper

Recent·Most cited

Time-Resolved Crystallography Reveals the Mechanisms of GTP hydrolysis for N-RAS and the Oncogenic Mutants G12C, G12V and Q61L

Guowu Lin, Paola Zinser Peniche, Xiaohong Zhou, Ulises Santiago, Igor V. Kurnikov, Silvia Russi, Brisa Caroline Alves Chagas, M.E. Sharpe, Dennis P. Stegmann, Shannon A. Heinig, Rohan K. Goyal, Veerappan Nagarajan, Daniel Calero, Sandra Viviana Vergara, Alexander Deiters, , Guillermo A. Calero

This study uses time-resolved crystallography to capture GTP hydrolysis intermediates of N-RAS and oncogenic mutants, revealing shared and distinct reaction mechanisms.

bioRxiv · Aug 21, 2025 · PreprintCancer Biology