Author

Harriet A. J. Saunders

University of Wisconsin–MadisonORCID 0000-0001-6953-4607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Anna S. AkhmanovaiD· 2 shared Kelly E. SteckeriD· 2 shared Stuart C. HowesiD· 2 shared Adela KarhanovaiD· 1 shared Alex Moore· 1 shared Andressa Pelster Jose· 1 shared Bei WangiD· 1 shared Christopher P. LapointeiD· 1 shared

Activity by Year

2017-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Anna S. AkhmanovaORCID

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4 papers

Recent·Most cited

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S. C. Gravett, Daan Morren, Harriet A. J. Saunders, Sung Ryul Choi, Andressa Pelster Jose, Adela Karhanova, Ioanna Metallidou, Alex Moore, Marel F.M. Spoelstra, Ruijie Liu, Matteo Giono, Saishree S. Iyer, J. Fernando Díaz, , Anna S. Akhmanova

This study shows taxanes induce conformational changes in microtubules, releasing GEF-H1 and activating RhoA signaling, leading to actin remodeling.

bioRxiv · Dec 23, 2025 · PreprintCell Biology

A network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth

Harriet A. J. Saunders, Cyntha M. van den Berg, Robin Hoogebeen, Donna Schweizer, Kelly E. Stecker, Ronald Roepman, Stuart C. Howes, Anna S. Akhmanova

The paper investigates the interactions of ciliary tip proteins and their role in microtubule dynamics, finding that they form structures that slow and processively elongate microtubules.

Nature Structural & Molecular Biology · Jan 24, 2025Peer-reviewedCell Biology

Light-induced trapping of endogenous proteins reveals spatiotemporal roles of microtubule and kinesin-1 in dendrite patterning of Drosophila sensory neurons

Yineng Xu, Bei Wang, Inle Bush, Harriet A. J. Saunders, Jill Wildonger, Chun Han

The paper introduces OptoTrap, a light-inducible system for manipulating endogenous proteins, and uses it to study microtubule and kinesin-1 roles in dendrite patterning in Drosophila sensory neurons.

bioRxiv · Sep 30, 2023 · PreprintDevelopmental Biology

Architecture and dynamics of overlapped RNA regulatory networks

Christopher P. Lapointe, Melanie A. Preston, Daniel Wilinski, Harriet A. J. Saunders, Zachary T. Campbell, Marvin Wickens

The paper studies the architecture and dynamics of overlapping RNA regulatory networks involving Puf3p, Puf4p, and Puf5p in yeast, revealing how competition and abundance influence network behavior.

RNA · Aug 2, 2017Peer-reviewedMolecular Biology