Author

S. A. Michaels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

K. K. Ojo· 3 shared A. M. Vaughan· 1 shared A. R. Paredez· 1 shared A.-L. B. G. Vigil· 1 shared B. G. K. Perera· 1 shared B. Zhang· 1 shared C. C. Sprenger· 1 shared D. J. Maly· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

K. K. Ojo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer

T. Uo, K. K. Ojo, C. C. Sprenger, K. S. Epilepsia, B. G. K. Perera, M. Damodarasamy, S. Sun, S. Kim, H. H. Hogan, M. A. Hulverson, R. Choi, G. R. Whitman, L. K. Barrett, S. A. Michaels, L. H. Xu, , S. R. Plymate

This paper evaluates a novel antiglycolytic compound, BKIDC-1553, showing selective growth inhibition of prostate cancer cells and safety for clinical trials.

bioRxiv · Jul 1, 2023Cancer Biology

Plasmodium falciparum Calcium Dependent Protein Kinase 4 is critical for male gametogenesis and transmission to the mosquito vector

S. KUMAR, M. T. Haile, M. R. Hoopmann, L. T. Tran, S. A. Michaels, S. R. Morrone, K. K. Ojo, L. M. Reynolds, U. Kusebauch, A. M. Vaughan, R. L. Moritz, S. H. I. Kappe, K. E. Swearingen

This study shows that PfCDPK4 is essential for male gametogenesis in Plasmodium falciparum, affecting exflagellation and parasite transmission to mosquitoes.

bioRxiv · Jun 6, 2021Microbiology

Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model

S. A. Michaels, H.-W. Shih, B. Zhang, E. D. Navaluna, Z. Zhang, R. M. Ranade, J. R. Gillespie, E. A. Merritt, E. Fan, F. S. Buckner, A. R. Paredez, K. K. Ojo

The paper develops a luciferase-based murine model and cell assay to evaluate the efficacy of MetRS inhibitor 1717 against Giardia lamblia, showing its potent in vivo activity.

bioRxiv · Oct 29, 2019Microbiology