Author

S. Alamos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Plant Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Research Focus:transcription & RNA processing· 2 Organism:Arabidopsis· 1 Approach:Bayesian inference· 1

Frequent Co-Authors

H. G. Garcia· 4 shared K. K. Niyogi· 2 shared Y. J. Kim· 2 shared A. Reimer· 1 shared B. Cheeseman· 1 shared B. Vianay· 1 shared D. Hansen· 1 shared E. Bearce· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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4 shared papersBiophysics

H. G. Garcia

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Author profile →

5 papers

Recent·Most cited

Optogenetic dissection of transcriptional repression in a multicellular organism

J. Zhao, N. C. Lammers, S. Alamos, Y. J. Kim, G. Martini, H. G. Garcia

This study uses optogenetics and mathematical modeling to show that the zinc-finger repressor Knirps rapidly and memorylessly represses gene expression by reducing transcriptional burst frequency.

Nature Communications · Oct 26, 2024Peer-reviewedBiophysics

Chromatin changes in PIF-regulated genes parallel their rapid transcriptional response to light

E. Gonzalez-Grandio, S. Alamos, Y. Zhang, J. Dalton-Roesler, K. K. Niyogi, H. G. Garcia, P. H. Quail

The paper identifies light-responsive genes regulated by PIF and shows that chromatin changes, specifically H3K9 acetylation, parallel rapid transcriptional responses to light.

bioRxiv · Oct 4, 2021 · PreprintPlant Biology

Quantitative imaging of RNA polymerase II activity in plants reveals the single-cell basis of tissue-wide transcriptional dynamics

S. Alamos, A. Reimer, K. K. Niyogi, H. G. Garcia

This study uses live-imaging to quantify RNA polymerase II activity in plant cells, revealing that transcriptional responses to stress involve changes in cell engagement rather than transcription rate.

bioRxiv · Aug 30, 2020Plant Biology

Real-time single-cell characterizationof the eukaryotic transcription cyclereveals correlations between RNAinitiation, elongation, and cleavage

J. Liu, D. Hansen, E. Eck, Y. J. Kim, M. A. Turner, S. Alamos, H. G. Garcia

This study uses Bayesian inference to analyze real-time single-cell transcription dynamics in fruit flies, revealing correlations between RNA initiation, elongation, and cleavage.

bioRxiv · Aug 29, 2020 · PreprintBiophysics

Variation in traction forces during cell cycle progression

B. Vianay, F. Senger, S. Alamos, M. Anjur-Dietrich, E. Bearce, B. Cheeseman, L. Lee, M. Thery

The paper measures traction forces during the cell cycle and finds they increase in G1, plateau in S phase, and decrease in G2, revealing a previously unknown regulation of cell contractility.

bioRxiv · Nov 1, 2017Cell Biology