Author

J. Ponce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Hinton· 2 shared A. Marshall· 2 shared B. Glancy· 2 shared B. Ueberheide· 2 shared E. D. Abel· 2 shared J. Shao· 2 shared K. Neikirk· 2 shared M. Mungai· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. Hinton

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2

S. Boopathy, B. E. Luce, C. M. Lugo, P. Hakim, J. L. McDonald, H. L. Kim, J. Ponce, B. Ueberheide, L. H. Chao

This study identifies interaction interfaces between SLC25A46 and mitochondrial fusion proteins Opa1 and Mfn2 using crosslinking mass-spectrometry and AlphaFold 2 modeling.

Journal of Biological Chemistry · Oct 1, 2024Peer-reviewedBiochemistry

Structure of an endogenous mycobacterial MCE lipid transporter

J. Chen, A. Fruhauf, C. Fan, J. Ponce, B. Ueberheide, G. Bhabha, D. C. Ekiert

The paper reports the cryo-EM structure of the Mce1 fatty acid import machine from Mycobacterium smegmatis, revealing its assembly and a previously unknown subunit, LucB.

bioRxiv · Dec 8, 2022Biochemistry

ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

A. Hinton, P. Katti, M. Mungai, D. Hall, O. Koval, J. Shao, Z. Vue, E. G. Lopez, R. Rostami, K. Neikirk, J. Ponce, J. Streeter, B. Schickling, S. Bacevac, C. Grueter, , E. D. Abel

This study shows that OPA1 deficiency in skeletal muscle increases MERC formation via ATF4, affecting calcium exchange and mitochondrial-ER tethering.

bioRxiv · Sep 12, 2022Biophysics

Systematic Transmission Electron Microscopy-Based Identification and 3D Reconstruction of Cellular Degradation Machinery

K. Neikirk, Z. Vue, P. Katti, B. I. Rodriguez, S. A. Omer, J. Shao, T. A. Christensen, E. Garza Lopez, A. Marshall, C. Palavicino-Maggio, J. Ponce, A. Alghanem, L. Vang, T. Barongan, H. Beasley, , A. Hinton

This paper describes methods to identify and distinguish subcellular structures involved in macroautophagy using TEM and 3D reconstruction, with applications to quantify degradation machinery under different conditions.

bioRxiv · Sep 26, 2021Biophysics

Spatial drivers and pre-cancer populations collaborate with the microenvironment in untreated and chemo-resistant pancreatic cancer

D. Cui Zhou, R. G. Jayasinghe, J. M. Herndon, E. Storrs, C.-K. Mo, Y. Wu, R. S. Fulton, M. A. Wyczalkowski, C. C. Fronick, L. A. Fulton, L. Thammavong, K. Sato, H. Zhu, H. Sun, L.-B. Wang, , Ch

This paper uses spatial single-cell omics to analyze PDAC tumors and microenvironment, identifying key populations and interactions that may inform treatment strategies.

bioRxiv · Jan 13, 2021Cancer Biology