Author

S. Brodesser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Mielenz· 2 shared F. Golombek· 2 shared K. Castiglione· 2 shared S. R. Schulz· 2 shared S. Urbanczyk· 2 shared A. Bozec· 1 shared A. C. Hausen· 1 shared A. Das· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

D. Mielenz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ERLIN1/2 scaffolds bridge TMUB1 and RNF170 and restrict cholesterol esterification to regulate the secretory pathway

M. Veronese, S. Kallabis, A. Kaczmarek, L. Robers, S. Schumacher, A. Das, A. Lofrano, S. Brodesser, S. Müller, K. Hofmann, M. Krüger, E. I. Rugarli

This study identifies ERLIN1/2 scaffolds that mediate TMUB1-RNF170 interactions, regulate cholesterol esterification, and maintain ER cholesterol levels to control Golgi morphology and the secretory pathway.

bioRxiv · Jan 17, 2024Cell Biology

Quantitative proteomics and lipidomics of TFG-deficient B cells provide insights into mechanisms of autophagic flux and plasma cell biology

T. D. Steinmetz, L. Reimann, S. R. Schulz, S. Urbanczyk, J. Thomas, A.-K. Himmelreich, F. Golombek, K. Castiglione, S. Brodesser, B. Warscheid, D. Mielenz

This study uses proteomics and lipidomics to analyze TFG-deficient B cells, identifying TFG's role in autophagy, plasma cell biology, and lipid homeostasis.

bioRxiv · Sep 1, 2022 · PreprintImmunology

Organ protection by caloric restriction depends on activation of the de novo NAD+ synthesis pathway

M. R. Spaeth, K. J. R. Hoyer-Allo, M. Johnsen, M. Hoehne, C. Lucas, S. Brodesser, J.-W. Lackmann, K. Kiefer, F. C. Koehler, P. Schiller, T. Kubacki, F. Grundmann, T. Benzing, B. Schermer, V. Burst, R.-U. Mueller

This study identifies KYNU-dependent de novo NAD+ biosynthesis as a mechanism by which caloric restriction protects against acute kidney injury in mice and humans.

bioRxiv · Aug 20, 2021Physiology

P2Y6 receptor signaling in natural killer cells impairs insulin sensitivity in obesity

A. Sieben, A. C. Hausen, P. Klemm, A. Jais, C. Heilinger, J. Alber, K. Folz-Donahue, L. Schumacher, J. Altmüller, M. Franitza, P. Giavalisco, Y. Hinze, S. Brodesser, C. Kukat, S. Theurich, J. C. Brüning

This study shows that blocking P2Y6R in NK cells improves insulin sensitivity in obese mice by reducing adipose tissue inflammation and glucose production.

bioRxiv · Jun 23, 2021 · PreprintImmunology

Mitochondrial function is essential for humoral immunity by controlling flux of the TCA cycle, phosphatidic acid and mTOR activity in B cells

S. Urbanczyk, O. Baris, J. Hofmann, F. Golombek, K. Castiglione, X. Meng, A. Bozec, D. Mougiakakos, S. R. Schulz, W. Schuh, U. Schloetzer-Schrehardt, T. Steinmetz, S. Brodesser, R. J. Wiesner, D. Mielenz

This study shows that mitochondrial function is critical for B cell differentiation into plasma cells by regulating TCA cycle flux, phosphatidic acid levels, and mTOR activity.

bioRxiv · Jan 14, 2021 · PreprintImmunology