Author

S. Brooks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Biochemistry· 1 Cell Biology· 1 Ecology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:mouse· 4 Approach:statistical model· 4 Assay:scRNA-seq· 3 Assay:ATAC-seq· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

S. Dell'Orso· 2 shared A. Anacleto· 1 shared A. Behensky· 1 shared A. C. Shetty· 1 shared A. Coulter· 1 shared A. Das· 1 shared A. E. Goldman· 1 shared A. Ward· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

S. Dell'Orso

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

E. Bagnoli, Y.-E. Lin, S. Burel, E. Jaimon, O. Antico, C. Themistokleous, J. Nikoloff, I. Morella, J. Watzlawik, F. Fiesel, W. Springer, F. Tonelli, S. Brooks, S. Dunnett, R. Brambilla, , M. Muqit

This study shows LRRK2 and PINK1 function in parallel neuroprotective pathways affecting ciliogenesis in Parkinson's disease, suggesting shared therapeutic targets.

bioRxiv · Jun 11, 2024Biochemistry

High-Resolution Spatial Transcriptomic Atlas of Mouse Soleus Muscle: Unveiling Single Cell and Subcellular Heterogeneity in Health and Denervation

J.-E. Hsu, L. Ruiz, Y. Hwang, S. Guzman, C.-S. Cho, W. Cheng, Y. Si, P. Macpherson, A. Anacleto, Q. Zhao, X. Zhao, M. Schrank, G. Jun, H.-M. Kang, M. Kim, , J. H. Lee

bioRxiv · Feb 26, 2024Physiology

Meta-metabolome ecology reveals that geochemistry and microbial functional potential are linked to organic matter development across seven rivers

R. E. Danczak, A. E. Goldman, M. A. Borton, R. K. Chu, J. G. Toyoda, V. A. Garayburu-Caruso, E. B. Graham, J. W. Morad, L. Renteria, J. R. Hager, S. Arnon, S. Brooks, E. Bar-Zeev, M. Jones, N. Jones, , J. C. Stegen

The paper links geochemistry and microbial functional potential to organic matter development across seven rivers using DOM characterization, geochemical analyses, and shotgun metagenomics.

bioRxiv · Jan 10, 2024 · PreprintEcology

Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss

N. Fernando, J. Gopalakrishnan, A. Behensky, L. Reich, C. Liu, V. Bass, M. Bono, W. Montgomery, R. De Pace, M. Mattapallil, V. Nagarajan, S. Brooks, D. Maric, R. Caspi, D. McGavern, H.-Y. Shih

This study identifies a unique CD8+ T cell population in AD mouse brains that contributes to amyloid beta-associated memory loss and shows that reducing these cells improves memory and reduces plaque formation.

bioRxiv · Mar 18, 2023 · PreprintImmunology

Single-cell analysis reveals the range of transcriptional states of circulating human neutrophils

G. Wigerblad, Q. Cao, S. Brooks, F. Naz, M. Gadkari, K. Jiang, S. Gupta, L. O'Neil, S. Dell'Orso, M. J. Kaplan, L. M. Franco

This study uses scRNA-seq to show that circulating human neutrophils are transcriptionally heterogeneous, forming four distinct clusters with distinct transcriptional states.

bioRxiv · Feb 22, 2022Immunology

Monocyte Subsets with High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8

A. Das, X. Wang, J. Kang, A. Coulter, A. C. Shetty, M. Bachu, S. Brooks, S. Dell'Orso, B. L. Foster, X. Fan, K. Ozato, M. Somerman, V. Thumbigere Math

The paper identifies monocyte subsets with high osteoclastogenic potential and shows IRF8 regulates their epigenetic and transcriptional programs.

bioRxiv · Jun 2, 2020Immunology

The expression of equine keratins K42 and K124 is restricted to the hoof epidermal lamellae of Equus caballus

C. Armstrong, L. Cassimeris, C. Da Silva Santos, Y. Micoogullari, B. Wagner, S. Babasyan, S. Brooks, H. GALANTINO-HOMER

The paper identifies K42 and K124 as lamellar-specific keratins in equine hooves and validates monoclonal antibodies against them.

bioRxiv · Jun 20, 2019Cell Biology