Author

S. J. Suijkerbuijk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

A. Krotenberg Garcia· 2 shared J. van Rheenen· 2 shared A. A. Khalil· 1 shared A. Fumagalli· 1 shared A. Krotenberg-Garcia· 1 shared C. Perez-Gonzalez· 1 shared D. Matic Vignjevic· 1 shared E. A. Strating· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

A. Krotenberg Garcia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanical regulation of cell fate transitions underlying colorectal cancer metastasis formation

M. C. van der Net, M. J. Vliem, L. J. S. Kemp, C. Perez-Gonzalez, E. A. Strating, A. Krotenberg-Garcia, R. M. Houtekamer, K. B. van den Anker, J. L. Monster, H. J. G. Snippert, A. A. Khalil, J. van Rheenen, S. J. Suijkerbuijk, O. Kranenburg, D. Matic Vignjevic, M. Gloerich

This study shows that mechanical signals from the Collagen I-rich matrix drive fate transitions in colorectal cancer cells, enabling metastasis despite lacking Lgr5 expression.

bioRxiv · Sep 17, 2023 · PreprintCancer Biology

Cell competition promotes metastatic intestinal cancer through a multistage process

A. Krotenberg Garcia, M. Ledesma-Terron, J. Vriend, M. E. van Luyk, S. J. Suijkerbuijk

This study shows that cell competition in the liver promotes metastatic intestinal cancer through a multistage process involving compaction, cell cycle arrest, differentiation, and reduced cellular fitness.

bioRxiv · Sep 14, 2023Cancer Biology

Active elimination of intestinal cells drives oncogenic growth in organoids

A. Krotenberg Garcia, A. Fumagalli, H. Quang Le, O. J. Sansom, J. van Rheenen, S. J. Suijkerbuijk

The paper shows cancer cells in organoids eliminate wild-type cells through apoptosis and JNK signaling, promoting their own growth by forcing cell death and fate change in competing cells.

bioRxiv · Nov 14, 2020Cancer Biology