Author

B. C. Selvanesan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Beck· 2 shared C. Gravekamp· 2 shared K. Meena· 2 shared A. Jahangir· 1 shared A. Maitra· 1 shared A. Patel· 1 shared A. Sagara· 1 shared D. Chandra· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Beck

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metabolic Reprogramming by Mutant GNAS Creates an Actionable Dependency in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Y. Makino, K. I. Rajapakshe, B. C. Selvanesan, T. Okumura, K. Date, P. Dutta, L. Abou-Elkacem, A. Sagara, J. Min, M. Sans, N. Yee, M. J. Siemann, J. Enriquez, P. Smith, P. Bhattacharya, , F. I. Thege

This study shows that mutant GNAS drives a gastric metaplasia gene signature and glycolytic dependency in IPMNs, offering a therapeutic target.

Gut · Sep 13, 2024Peer-reviewedCancer Biology

Tumor-targeted delivery of childhood vaccine recall antigens by attenuated Listeria reduces pancreatic cancer

B. C. Selvanesan, D. Chandra, W. Quispe-Tintaya, A. Jahangir, A. Patel, K. Meena, R. Alberto Alves Da Silva, M. Friedman, J. Li, S. Siddiqui, S. K. Libutti, Z. Yuan, A. Beck, L. Tesfa, W. Koba, , C. Gravekamp

This study shows that delivering a childhood vaccine antigen via attenuated Listeria improves immunotherapy for pancreatic cancer by converting cold tumors into hot tumors and enhancing T cell activity.

bioRxiv · Jun 4, 2021 · PreprintImmunology

Nicotinamide combined with gemcitabine is an immunomodulatory therapy that restrains pancreatic cancer in mice

B. C. Selvanesan, K. Meena, A. Beck, L. Meheus, O. Lara, I. Rooman, C. Gravekamp

This study shows that combining nicotinamide with gemcitabine reduces pancreatic tumor growth and improves survival in mice by modulating the immune microenvironment.

bioRxiv · Jun 2, 2020Immunology