Author

S. Koska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:development & morphogenesis· 3 Organism:bacteria (other)· 2 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

M. Domazet-Loso· 3 shared M. Futo· 3 shared N. Corak· 3 shared T. Domazet-Loso· 3 shared A. Pahl· 2 shared A. Tusar· 2 shared H. Waldmann· 2 shared J. Warmers· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersEvolutionary Biology

M. Domazet-Loso

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Somatic embryogenesis of grapevine (Vitis vinifera) expresses a transcriptomic hourglass

S. Koska, D. Leljak-Levanic, N. Malenica, K. Bigovic Villi, M. Futo, N. Corak, M. Jagic, A. Tusar, N. Kasalo, M. Domazet-Loso, K. Vlahovicek, T. Domazet-Loso

The paper investigates whether the hourglass-shaped ontogeny-phylogeny correlation observed in Arabidopsis zygotic embryogenesis is preserved in grapevine somatic embryogenesis, finding that the heart stage has the most conserved transcriptome.

bioRxiv · Apr 8, 2024Evolutionary Biology

Detection of a Mitochondrial Stress Phenotype using the Cell Painting Assay

S. Rezaei Adariani, D. Agne, S. Koska, A. Burhop, J. Warmers, P. Janning, M. Metz, A. Pahl, S. Sievers, H. Waldmann, S. Ziegler

The paper shows that the Cell Painting assay can detect mitochondrial stress and predict mitochondrial toxicity in small molecules.

bioRxiv · Nov 8, 2023 · PreprintCell Biology

Illuminating Dark Chemical Matter using the Cell Painting Assay

A. Pahl, J. Liu, S. Patil, S. Rezaei Adariani, B. Scholermann, J. Bonowski, S. Koska, S. Sievers, J. Warmers, S. Ziegler, H. Waldmann

The paper uses the Cell Painting Assay to identify bioactive compounds in dark chemical matter, revealing modulators of microtubules, DNA synthesis, and pyrimidine biosynthesis.

bioRxiv · May 31, 2023Cell Biology

Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors

L. Goebel, T. Kirschner, S. Koska, A. Rai, P. Janning, S. Maffini, H. Vatheuer, P. Czodrowski, R. S. Goody, M. P. Mueller, D. Rauh

This study designs and evaluates nucleotide-based covalent inhibitors for KRasG13C, showing they block nucleotide exchange and oncogenic signaling.

bioRxiv · Jul 25, 2022Cancer Biology

A novel time-lapse imaging method for studying developing bacterial biofilms

M. Futo, T. Siroki, S. Koska, N. Corak, A. Tusar, M. Domazet-Loso, T. Domazet-Loso

The paper introduces an Arduino-based time-lapse imaging method to visualize complete bacterial biofilm ontogeny, overcoming challenges like water condensation during recording.

bioRxiv · Jun 24, 2022 · PreprintMicrobiology

Embryo-like features in developing Bacillus subtilis biofilms

M. Futo, L. Opasic, S. Koska, N. Corak, T. Siroki, V. Ravikumar, A. Thorsell, D. Kifer, M. Domazet-Loso, K. Vlahovicek, I. Mijakovic, T. Domazet-Loso

This paper shows that Bacillus subtilis biofilm development mirrors evolutionary patterns, with gene expression and morphology resembling embryonic stages.

bioRxiv · Mar 9, 2020Evolutionary Biology