Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
A. Voigt, H. Kampen, E. Heuser, S. Zeiske, B. Hoffmann, D. Hoeper, M. Holsteg, F. Sick, S. Ziegler, K. Wernike, M. Beer, D. Werner
Bluetongue virus serotype 3 was detected in Culicoides biting midges in Germany in October 2023, coinciding with its emergence in ruminants and the presence of Schmallenberg virus in midge pools.
bioRxiv · Feb 26, 2024 · PreprintMicrobiology
L. Doetsch, C. Davies, E. Hennes, J. Schoenfeld, A. Kumar, C. Da Cruz Lopes Guita, J. H. M. Ehrler, K. Hiesinger, S. Thavam, P. Janning, S. Sievers, S. Knapp, E. Proschak, S. Ziegler, H. Waldmann
The paper identifies epoxykynin as a potent sEH inhibitor that modulates the kynurenine pathway, offering new opportunities to address cancer-induced immune tolerance.
bioRxiv · Nov 9, 2023Cell Biology
S. Rezaei Adariani, D. Agne, S. Koska, A. Burhop, J. Warmers, P. Janning, M. Metz, A. Pahl, S. Sievers, H. Waldmann, S. Ziegler
The paper shows that the Cell Painting assay can detect mitochondrial stress and predict mitochondrial toxicity in small molecules.
bioRxiv · Nov 8, 2023 · PreprintCell Biology
A. Pahl, J. Liu, S. Patil, S. Rezaei Adariani, B. Scholermann, J. Bonowski, S. Koska, S. Sievers, J. Warmers, S. Ziegler, H. Waldmann
The paper uses the Cell Painting Assay to identify bioactive compounds in dark chemical matter, revealing modulators of microtubules, DNA synthesis, and pyrimidine biosynthesis.
bioRxiv · May 31, 2023Cell Biology
L. Zhang, J. Yu, S. Spath, S. Sheoran, D. Bejarano, M. Vandestienne, A.-K. Weier, T. Quast, M. Ibrahim, S. Reimer, S. Uderhardt, E. Mass, J. Hasenauer, A. Pfeifer, E. Kiermaier, , A. Schlitzer
This study identifies GPR183 as a key receptor guiding CD301b+ cDC2 to a TSLP-dependent survival niche in the lung adventitial cuff.
bioRxiv · Aug 28, 2022 · PreprintImmunology
A. Pahl, B. Schoelermann, M. Rusch, M. Dow, C. Hedberg, A. Nelson, S. Sievers, H. Waldmann, S. Ziegler
This paper introduces subprofile analysis to predict the mode of action of small molecules using morphological profiling data, enabling rapid bioactivity annotation without requiring extensive reference compounds.
bioRxiv · Aug 15, 2022Cell Biology
M. Stirm, L. M. Fonteyne, B. Shashikadze, M. Lindner, M. Chirivi, A. Lange, C. Kaufhold, C. Mayer, I. Medugorac, B. Kessler, M. Kurome, V. Zakhartchenko, A. Hinrichs, E. Kemter, S. Krause, , E. Wolf
This paper develops a scalable pig model for Duchenne muscular dystrophy by breeding DMD carriers, enabling large cohorts for disease mechanism studies and therapeutic testing.
Disease Models & Mechanisms · Dec 1, 2021Peer-reviewedPathology
L. So, K. Obata-Ninomiya, A. Hu, V. Muir, A. Takamori, J. Song, J. H. Buckner, R. Savan, S. Ziegler
This study shows regulatory T cells suppress CD4 T cell activation by inhibiting translation of mRNAs encoding protein synthesis machinery, highlighting translational control in immune tolerance.
bioRxiv · Sep 23, 2021Immunology