Author

S. L. Jaspersen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:yeast· 7 Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 5 Research Focus:cell type annotation· 5 Approach:microscopy & imaging analysis· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

J. M. Varberg· 3 shared J. R. Unruh· 3 shared S. E. Smith· 3 shared Z. Yu· 3 shared J. M. Gardner· 2 shared J. Unruh· 2 shared S. McCroskey· 2 shared A. J. Bestul· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

J. M. Varberg

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Author profile →

7 papers

Recent·Most cited

Meiotic Nuclear Pore Complex Remodeling Provides Key Insights into Nuclear Basket Organization

G. A. King, R. Wettstein, J. M. Varberg, K. Chetlapalli, M. E. Walsh, L. Gillet, C. Hernandez-Armenta, P. Beltrao, R. Aebersold, S. L. Jaspersen, J. Matos, E. Unal

The paper identifies two distinct nuclear pore complex remodeling events during budding yeast meiosis, revealing conserved mechanisms of nuclear basket organization.

bioRxiv · Apr 14, 2022Cell Biology

Comprehensive Structure and Functional Adaptations of the Yeast Nuclear Pore Complex

C. Akey, D. Singh, C. Ouch, I. Echeverria, I. Nudelman, J. M. Varberg, Z. Yu, F. Fang, Y. Shi, J. Wang, D. Saltzberg, K. Song, C. Xu, J. Gumbart, S. Suslov, , M. Rout

This study presents the structure of the yeast nuclear pore complex using cryo-EM, revealing its functional adaptations and evolutionary links.

bioRxiv · Oct 29, 2021Biophysics

A distinct inner nuclear membrane proteome in Saccharomyces cerevisiae gametes

S. N. Shelton, S. E. Smith, J. R. Unruh, S. L. Jaspersen

The paper identifies a distinct inner nuclear membrane proteome in yeast gametes, showing unique gene expression and protein composition compared to mitotic cells.

bioRxiv · Aug 2, 2021Cell Biology

Redistribution of centrosomal proteins by centromeres and Polo kinase controls partial nuclear envelope breakdown in fission yeast

A. J. Bestul, Z. Yu, J. R. Unruh, S. L. Jaspersen

The paper shows that centromere linkage to the SPB drives redistribution of Sad1 and Plo1 activation, facilitating partial NEBD and spindle formation in fission yeast.

bioRxiv · Dec 1, 2020Cell Biology

High-throughput identification of nuclear envelope protein interactions in Schizosaccharomyces pombe using an arrayed membrane yeast-two hybrid library

J. M. Varberg, J. M. Gardner, S. McCroskey, S. Saravanan, W. D. Bradford, S. L. Jaspersen

The paper develops a high-throughput method to identify nuclear envelope protein interactions in fission yeast using a membrane yeast-two hybrid system.

bioRxiv · Jul 29, 2020Cell Biology

Asi1 regulates the distribution of proteins at the inner nuclear membrane in Saccharomyces cerevisiae

C. J. Smoyer, S. E. Smith, S. McCroskey, J. Unruh, S. L. Jaspersen

This study shows Asi1 regulates INM protein distribution by removing mis-targeted proteins and controlling native components like Pom33 through ubiquitination.

bioRxiv · Oct 14, 2018Cell Biology

Membrane insertion function for SUN-KASH complex revealed by high resolution analysis of yeast centrosomes

J. Chen, J. M. Gardner, Z. Yu, S. E. Smith, S. McKinney, B. D. Slaughter, J. R. Unruh, S. L. Jaspersen

The paper uses high-resolution imaging to reveal the structure and function of the SUN-KASH complex in yeast centrosome insertion, identifying Mps3 as a fifth SPIN component and a novel LINC complex.

bioRxiv · Sep 10, 2018Cell Biology