Author

S. Lonial

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2

Frequent Co-Authors

F. E.-H. Lee· 3 shared I. Sanz· 3 shared J. Andrews· 3 shared C. J. Joyner· 2 shared C. Saney· 2 shared C. Tipton· 2 shared D. C. Nguyen· 2 shared G. Gibson· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

F. E.-H. Lee

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Multi-Niche Human Bone Marrow On-A-Chip for Studying the Interactions of Adoptive CAR-T Cell Therapies with Multiple Myeloma

D. Ghoshal, I. Petersen, R. Ringquist, L. Kramer, E. Bhatia, T. Hu, A. Richard, R. Park, J. Corbin, S. Agarwal, A. Thomas, S. Ramirez, J. Tharayil, E. Downey, F. Ketchum, , K. Roy

This study develops a 3D bone marrow-on-a-chip model to investigate interactions between CAR-T cells and multiple myeloma cells in different niches and assess therapeutic responses.

bioRxiv · Apr 8, 2024 · PreprintCancer Biology

Majority of human circulating plasmablasts stop blasting: A probable misnomer

D. C. Nguyen, C. Saney, I. T. Hentenaar, M. Cabrera-Mora, M. C. Woodruff, J. Andrews, S. Lonial, I. Sanz, F. E.-H. Lee

The study shows most blood plasmablasts are not actively dividing, suggesting the term 'plasmablast' may be misleading.

bioRxiv · Sep 10, 2023 · PreprintImmunology

Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity

A. Moreno, K. Manning, M. I. Azeem, A. K. Nooka, M. Ellis, R. J. Manalo, J. M. Switchenko, B. Wali, J. L. Kaufman, C. C. Hofmeister, N. S. Joseph, S. Lonial, K. M. Dhodapkar, M. V. Dhodapkar, M. S. Suthar

This study examines how SARS-CoV-2 booster vaccines affect antibody profiles in myeloma patients, finding improved binding but not neutralization against variants.

bioRxiv · Aug 17, 2023 · PreprintImmunology

Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses

M. Duan, D. C. Nguyen, C. J. Joyner, C. Saney, C. Tipton, J. Andrews, S. Lonial, C. Kim, I. Hentenaar, A. Kosters, E. Ghosn, A. Jackson, S. Knechtle, S. Maruthamuthu, S. Chandran, , F. E.-H. Lee

The study maps human bone marrow plasma cell heterogeneity using single-cell transcriptomics, revealing maturation pathways and molecular features of long-lived plasma cells.

bioRxiv · Jan 18, 2023 · PreprintImmunology

Retrotransposons facilitate tissue-specific horizontal Transfer of circulating tumor DNA

M. cinar, L. Martinez-Medina, P. K. Puvvula, A. Arakelyan, B. N. Vardarajan, N. Anthony, G. P. Nagaraju, D. Park, L. Feng, F. Sheff, M. Mosunjac, D. Saxe, S. Flygare, O. B. Alese, J. Kaufman, , L. Bernal-Mizrachi

This study shows retrotransposons enable tissue-specific horizontal gene transfer of circulating tumor DNA in cancer cells, influencing treatment response and opening new therapeutic avenues.

bioRxiv · Aug 10, 2022 · PreprintCancer Biology

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

X. Mo, Q. Niu, A. A. Ivanov, Y. H. Tsang, C. Tang, C. Shu, A. Wahafu, S. Doyle, D. Cicka, X. Yang, D. Fan, M. A. Reyna, L. A. D. Cooper, C. S. Moreno, W. Zhou, , H. Fu

The paper identifies mutation-directed neo-protein-protein interactions in cancer using a high-throughput screening platform, revealing therapeutic opportunities through neo-interaction rewiring.

bioRxiv · Oct 3, 2021Cancer Biology

Maturation of Human Long-lived Plasma Cells Results in Resistance to Apoptosis by Transcriptional and Epigenetic Regulation

C. J. Joyner, A. Ley, D. Nguyen, M. Ali, A. Corrado, C. Tipton, C. Scharer, T. Mi, M. C. Woodruff, J. Hom, J. M. Boss, M. Duan, G. Gibson, D. Roberts, J. Andrews, , F. E.-H. Lee

This study shows human blood ASCs undergo transcriptional and epigenetic changes in the BM microniche to become apoptotic-resistant LLPC.

bioRxiv · May 22, 2021 · PreprintImmunology