S. Ngo

Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli .

The paper shows that A-rich first six codons in E. coli mRNAs enhance translation initiation and stability, leading to higher protein expression.

Global regulation via modulation of ribosome pausing by the ABC-F protein EttA

The paper shows that the ABC-F protein EttA modulates ribosome pausing to regulate protein expression and cell growth by rescuing ribosomes at specific negatively charged amino acid sequences.

Arylamine N-acetyltransferase-1 reveals a subpopulation of ALS patients with altered metabolic capacity

The paper identifies a subpopulation of ALS patients with altered metabolic capacity linked to NAT1 activity, showing higher metabolic indices and faster disease progression.

IL-33-induced neutrophilic inflammation and NETosis underlie rhinovirus-triggered exacerbations of asthma

This study identifies IL-33 as a key driver of neutrophilic inflammation and NETosis in rhinovirus-induced asthma exacerbations, showing that blocking IL-33 reduces exacerbation severity.

Regulation of the macrolide resistance ABC-F translation factor MsrD

The paper investigates how MsrD, an ABC-F translation factor, regulates macrolide resistance in streptococci by interacting with the ribosome and preventing transcriptional attenuation.