Author

S. O'Connell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 1 Plant Biology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 7 Organism:non-human primate· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

T. S. Johnston· 5 shared A. Choi· 4 shared A. Cook· 4 shared A. Dodson· 4 shared E. Lamb· 4 shared L. Lai· 4 shared M. Gagne· 4 shared M. Koch· 4 shared

Activity by Year

2021-2023 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

T. S. Johnston

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Immune memory shapes human polyclonal antibody responses to H2N2 vaccination

Y. R. Yang, J. Han, H. R. Perrett, S. T. Richey, A. M. Jackson, A. J. Rodriguez, R. A. Gillespie, S. O'Connell, J. E. Raab, L. Y. Cominsky, A. Chopde, M. Kanekiyo, K. V. Houser, G. L. Chen, A. B. McDermott, , A. B. Ward

This study examines how prior H2 influenza exposure influences polyclonal antibody responses to H2N2 vaccination, showing differences in epitope targeting between H2-exposed and H2-naive individuals.

bioRxiv · Aug 23, 2023Immunology

A baseline for the genetic stock identification of Atlantic herring, Clupea harengus, in ICES Divisions 6.a, 7.b-c

E. D. Farrell, L. Andersson, D. Bekkevold, N. Campbell, J. Carlsson, M. W. Clarke, A. Egan, A. Folkvord, M. Gras, S. Maersk Lusseau, S. Mackinson, C. Nolan, S. O'Connell, M. O'Malley, M. Pastoors, , E. White

The paper develops a genetic assignment method using SNPs to identify Atlantic herring populations in ICES Divisions 6.a, 7.b-c with high accuracy.

bioRxiv · Apr 7, 2022Zoology

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones

N. S. Lima, M. Musayev, T. S. Johnston, D. A. Wagner, A. R. Henry, L. Wang, E. S. Yang, Y. Zhang, K. Birungi, W. P. Black, S. O'Dell, S. D. Schmidt, D. Moon, C. G. Lorang, B. Zhao, , P. D. Kwong

The paper examines antibody responses to SARS-CoV-2 variants, finding convergent epitope specificities, V gene usage, and public B cell clones across different variants.

bioRxiv · Mar 28, 2022Immunology

A mechanistic investigation of enhanced nitrogen use efficiency in wheat seedlings after treatment with a precision engineered Ascophyllum nodosum biostimulant

L. Langowski, O. Goni, E. Ikuyinminu, E. Feeney, S. O'Connell

This study investigates how a precision-engineered seaweed biostimulant enhances nitrogen use efficiency in wheat seedlings through transcriptional and biochemical changes.

bioRxiv · Dec 10, 2021 · PreprintPlant Biology

Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

K. S. Corbett, M. Gagne, D. Wagner, S. O'Connell, S. R. Narpala, D. R. Flebbe, S. F. Andrew, R. L. Davis, B. Flynn, T. S. Johnston, C. Stringham, L. Lai, D. Valentin, A. Van Ry, Z. Flinchbaugh, , A Pekosz

mRNA-1273 boosted nonhuman primates show increased neutralizing antibody responses and protection against SARS-CoV-2 beta variant infection.

bioRxiv · Aug 11, 2021 · PreprintImmunology

Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates

K. S. Corbett, A. Werner, S. O'Connell, M. Gagne, L. Lai, J. Moliva, B. Flynn, A. Choi, M. Koch, K. E. Foulds, S. Andrew, D. Flebbe, E. Lamb, S. T. Nurmukhambetova, S. Provost, , M. Suthar

This study evaluates mRNA-1273 vaccine efficacy against SARS-CoV-2 B.1.351 in nonhuman primates, finding that two doses significantly reduce viral replication in the airways.

bioRxiv · May 21, 2021 · PreprintImmunology

Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates

K. S. Corbett, M. C. Nason, B. Flach, M. Gagne, S. O'Connell, T. S. Johnston, S. N. Shah, V. V. Edara, K. Floyd, L. Lai, C. McDanal, J. R. Francica, B. Flynn, K. Wu, A. Choi, , Leung

This study shows that mRNA-1273 vaccine-induced antibody responses correlate with protection against SARS-CoV-2 infection in nonhuman primates.

bioRxiv · Apr 20, 2021 · PreprintImmunology

Variant SARS-CoV-2 mRNA vaccines confer broad neutralization as primary or booster series in mice

K. Wu, A. Choi, M. Koch, S. Elbashir, L. Ma, D. Lee, A. Woods, C. Henry, C. Palandjian, A. Hill, H. Jani, J. Quinones, N. Nunna, S. O'Connell, A. B. McDermott, , D. K. Edwards

This study evaluates updated SARS-CoV-2 mRNA vaccines in mice, showing that mRNA-1273.351 boosts neutralization against B.1.351 and mRNA-1273.211 provides broad cross-variant protection.

bioRxiv · Apr 13, 2021Microbiology

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

J. R. Francica, B. J. Flynn, K. E. Foulds, A. T. Noe, A. P. Werner, I. N. Morre, M. Gagne, T. S. Johnston, C. Tucker, R. L. Davis, B. Flach, S. O'Connell, S. F. Andrew, E. Lamb, D. R. Flebbe, , McDermott

This study shows that an AS03-adjuvanted SARS-CoV-2 spike protein vaccine induces strong antibody responses and protects nonhuman primates from viral challenge.

bioRxiv · Mar 2, 2021 · PreprintImmunology