Author

S. S. D'Souza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:non-human primate· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Kumar· 2 shared I. I. Slukvin· 2 shared C. M. Capitini· 1 shared H. Kang· 1 shared J. A. Thomson· 1 shared J. Coonen· 1 shared J. Maufort· 1 shared J. T. Weinfurter· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

A. Kumar

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2 papers

Recent·Most cited

Generation of SIV resistant T cells and Macrophages from Nonhuman Primate Induced Pluripotent Stem Cells with Edited CCR5 locus

S. S. D'Souza, A. Kumar, J. Weinfurter, M. A. Park, J. Maufort, L. Tao, H. Kang, T. Golos, J. A. Thomson, M. Reynolds, I. I. Slukvin

This study generates CCR5-edited T cells and macrophages from nonhuman primate iPSCs, showing resistance to SIV replication.

bioRxiv · May 3, 2021Cell Biology

MHC-matched allogeneic bone marrow transplant fails to eliminate SHIV-infected cells from ART-suppressed Mauritian cynomolgus macaques

J. T. Weinfurter, S. S. D'Souza, L. M. Matschke, S. Bennett, L. E. Kelnhofer-Millevolte, K. Suknuntha, A. Kumar, J. Coonen, C. M. Capitini, P. Hematti, T. G. Golos, I. I. Slukvin, M. R. Reynolds

This study shows that MHC-matched allogeneic bone marrow transplants in ART-suppressed SHIV-infected macaques do not fully eliminate viral reservoirs, with persistent SHIV DNA in tissues and rebound after ART interruption.

bioRxiv · Apr 16, 2021 · PreprintImmunology