Author

S. Shiekh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

H. Balci· 3 shared G. Mustafa· 2 shared M. E. Hoque· 2 shared S. G. Kodikara· 2 shared A. Jack· 1 shared A. Patterson· 1 shared A. Yildiz· 1 shared B. Bothner· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

H. Balci

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Impact of Shelterin Complex on Telomere Accessibility

S. Shiekh, A. Jack, G. Mustafa, S. G. Kodikara, P. Gyawali, M. E. Hoque, A. Yildiz, H. Balci

The paper measures how POT1 and a four-component shelterin complex affect telomere accessibility using PNA probes and FRET-PAINT, finding shelterin provides stronger protection than POT1 alone.

bioRxiv · May 24, 2022 · PreprintBiophysics

Rtt105 configurationally staples RPA and blocks facilitated exchange and interactions with RPA-interacting proteins

S. Kuppa, J. Deveryshetty, R. Chadda, J. Mattice, N. Pokhrel, V. Kaushik, A. Patterson, N. Dhingra, S. Pangeni, M. K. Sadauskas, S. Shiekh, H. Balci, T. Ha, X. Zhao, B. Bothner, E. Antony

This study shows Rtt105 binds to RPA, staples it, and blocks RIP interactions without ssDNA, while stabilizing RPA-ssDNA filaments with ssDNA.

bioRxiv · Feb 5, 2022 · PreprintBiochemistry

Emerging Accessibility Patterns in Long Telomeric Overhangs

S. Shiekh, G. Mustafa, S. G. Kodikara, M. E. Hoque, E. Yokie, J. J. Portman, H. Balci

The paper investigates accessibility patterns in human telomeric overhangs using single-molecule experiments and computational modeling, revealing periodic accessibility changes related to G-quadruplex folding.

bioRxiv · Nov 24, 2021 · PreprintBiophysics