S. Tanaka

The paper identifies the Sld3-Esa1 interaction as a regulatory mechanism that alleviates gene silencing and promotes activation of late and dormant replication origins in yeast.

Passive head motion reduces blood pressure in hypertensive rats and humans by decreasing AT1R expression in RVLM astrocytes through interstitial fluid shear stress.

The paper develops a hybrid simulation method to study multimeric protein complex disassembly, revealing new dissociation events and key residues for oligomer stability.

This study shows that myristate supports asymbiotic growth of arbuscular mycorrhizal fungi by serving as a carbon and energy source.

This paper describes a bivalent hAd5 vaccine combining S-Fusion and N-ETSD antigens that elicits strong Th1-biased T-cell and neutralizing antibody responses in pre-clinical models.

The paper investigates how epigenetic regulation loss leads to genetic fixation of novel traits in medaka fish through methylation profiling and CRISPR/Cas9 deletion.

This study analyzes multi-omics data from activated synovial fibroblasts to identify genetic risk factors and potential drug targets for rheumatoid arthritis.

The paper develops a high-throughput method to evaluate BRCA2 variants of unknown significance, classifying 186 variants into neutral, intermediate, or deleterious categories with high sensitivity and specificity.