Author

S. Tavazoie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2

Frequent Co-Authors

H. Alwaseem· 2 shared A. Cardenas· 1 shared A. Higgins-Chen· 1 shared A. Ketcham· 1 shared A. Monzel· 1 shared A. Pinzaru· 1 shared A. Towheed· 1 shared B. A. Kaufman· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. Alwaseem

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Arginine limitation causes a directed DNA sequence evolution response in colorectal cancer cells

D. Hsu, J. Gao, N. Yamaguchi, A. Pinzaru, N. Mandayam, M. Liberti, S. Heissel, H. Alwaseem, S. Tavazoie, S. Tavazoie

This study shows that arginine limitation in colorectal cancer cells drives DNA sequence evolution away from arginine codons, leading to altered proteins.

bioRxiv · Jan 2, 2023 · PreprintCancer Biology

Intracellular acidification is a hallmark of thymineless death in E. coli

A. Ketcham, P. Freddolino, S. Tavazoie

The paper identifies intracellular acidification as a key causal factor in thymineless death in E. coli, showing it reduces cell viability when pH is increased.

bioRxiv · Apr 4, 2022Microbiology

OxPhos Dysfunction Causes Hypermetabolism and Reduces Lifespan in Cells and in Patients with Mitochondrial Diseases

G. Sturm, K. R. Karan, A. Monzel, B. S. Santhanham, T. Taivassalo, C. Bris, S. A. Duplaga, M. Cross, A. Towheed, A. Higgins-Chen, M. J. McManus, A. Cardenas, J. Lin, E. S. Epel, S. Rahman, , M. Picard

The paper shows that OxPhos dysfunction leads to hypermetabolism and reduced lifespan in cells and mitochondrial disease patients.

bioRxiv · Nov 29, 2021Cell Biology

A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of bound metabolic mRNAs

X. Liu, H. Alwaseem, H. Molina, B. Tavora, S. Tavazoie

The paper identifies a tRNA fragment that promotes Nucleolin oligomerization and stabilizes metabolic mRNAs, enhancing breast cancer metastasis.

bioRxiv · Apr 26, 2021 · PreprintCancer Biology