Author

S. Wigfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Aulicino· 1 shared A. L. Harris· 1 shared A. Mcintyre· 1 shared A. Simmons· 1 shared A. Valli· 1 shared B. M. Kessler· 1 shared D. C. I. Goberdhan· 1 shared D. Corridoni· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Aulicino

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2 papers

Recent·Most cited

Ataxin-3 links NOD2 and TLR2 mediated innate immune sensing and metabolism in myeloid cells

T. Chapman, D. Corridoni, S. Shiraishi, S. Pandey, A. Aulicino, S. Wigfield, M. do Carmo Costa, M.-L. Thezenas, H. Paulson, R. Fischer, B. M. Kessler, A. Simmons

This study identifies ataxin-3 as a mediator of NOD2 and TLR2 signaling in myeloid cells, linking innate immune sensing to metabolic processes and mitochondrial function.

bioRxiv · Apr 1, 2019Immunology

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine-resistance in breast cancer

M. Morotti, E. Bridges, A. Valli, H. Choudhry, H. Sheldon, S. Wigfield, N. Gray, D. Jones, E. J. Teoh, W.-C. Cheng, S. Lord, S. Haider, A. Mcintyre, D. C. I. Goberdhan, F. Buffa, A. L. Harris

This study shows hypoxia shifts SNAT2 regulation from ER to HIF-1 in breast cancer, leading to endocrine resistance and poor outcomes.

bioRxiv · Aug 3, 2018Cancer Biology