Author

S. Zuryn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Ahier· 1 shared A. Marzio· 1 shared B. M. Collins· 1 shared B. Townsend· 1 shared C.-Y. Dai· 1 shared G. Nguyen-Dien· 1 shared J. Götz· 1 shared J. Pagan· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Ahier

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Author profile →

2 papers

Recent·Most cited

FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors

J. Pagan, G. Nguyen-Dien, K. Kozul, Y. Cui, B. Townsend, S. S. Ooi, M. Pagano, M. Lazarou, R. Taylor, B. M. Collins, R. G. Parton, P. Kulkarni, N. Carrodus, S. Zuryn, S. Millard, , M. Jones

This study identifies FBXL4 as a suppressor of basal mitophagy by ubiquitylating and degrading NIX and BNIP3, and shows pathogenic variants disrupt this function leading to mtDNA depletion syndrome.

bioRxiv · Oct 12, 2022Cell Biology

PINK1-parkin-mediated mitophagy generates stereotyped somatic mosaicism of the mitochondrial genome

A. Ahier, N. Cummins, C.-Y. Dai, J. Götz, S. Zuryn

The paper shows that PINK1 and parkin influence mitophagy, leading to tissue-specific differences in mitochondrial DNA mutation levels in C. elegans.

bioRxiv · Jun 12, 2020Cell Biology