Author

S.-I. Saitoh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Fujita· 2 shared K. Miyake· 2 shared M. Komine· 2 shared M. Ohtsuki· 2 shared M. Taoka· 2 shared N. Yoshida· 2 shared R. Fukui· 2 shared R. Sato· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

E. Fujita

Mutual co-authors in cluster

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2 papers

Recent·Most cited

TLR7/8 stress response drives histiocytosis in SLC29A3 disorders

K. Miyake, T. Shibata, R. Sato, M. Taoka, S.-I. Saitoh, M. Komine, K. Yamaguchi, S. Goyama, Y. Motoi, J. Kitaura, K. Izawa, Y. Yamauchi, Y. Tsukamoto, T. Ichinohe, E. Fujita, , T. Taguchi

This study identifies TLR7/8 as drivers of histiocytosis in SLC29A3 disorders by responding to lysosomal nucleoside stress and enhancing monocyte proliferation and phagocyte maturation.

bioRxiv · Oct 27, 2022Immunology

Nucleosides drive histiocytosis in SLC29A3 disorders by activating TLR7

T. Shibata, M. Taoka, S.-I. Saitoh, Y. Yamauchi, Y. Motoi, M. Komine, E. Fujita, R. Sato, H. Sagara, T. Ichinohe, M. Kawazoe, C. Kato, K. Furusho, Y. Murakami, R. Fukui, , K. MIYAKE

This study shows that TLR7 activation by accumulated nucleosides in lysosomes drives histiocytosis in SLC29A3 disorders.

bioRxiv · Dec 16, 2019 · PreprintImmunology