Author

S.-K. Lee

University at Buffalo, State University of New York

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

C. A. Schiffer· 2 shared E. Spielvogel· 2 shared R. Swanstrom· 2 shared Y. Park· 2 shared A. Ali· 1 shared A. Rogers· 1 shared A. Sondgeroth· 1 shared C. W. Carter· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

C. A. Schiffer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

KMT2d regulates tooth enamel development

Jung-Mi Lee, H. Jung, Q. Tang, L. Li, S.-K. Lee, Seunghee Lee, Y. Park, Hyuk-Jae Edward Kwon

This study investigates the role of KMT2D in amelogenesis using a conditional knockout mouse model, revealing its critical role in enamel development and identifying direct target genes involved in ameloblast differentiation.

Journal of Dental Research · Mar 18, 2025Peer-reviewedDevelopmental Biology

Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex

K. Min, S. Chung, S.-K. Lee, J. Lee, P. T. Toi, D. Kim, J. S. Lee, J.-Y. Park

This study uses MRI to measure responses of cultured cells and in vivo rat cortex to ionic solutions that modulate membrane potential, finding changes in T2 relaxation time and bound-to-free water proton ratio.

bioRxiv · Apr 2, 2024Biophysics

Antibody-conjugating nanogel (Conjugel) with two immune checkpoint inhibitors for enhanced cancer immunotherapy

Y. J. Chae, K.-G. Lee, D. Oh, S.-K. Lee, Y. Park, J. Kim

This study develops a nanogel-based system that delivers two immune checkpoint inhibitors, enhancing cancer immunotherapy efficacy and reducing toxicity compared to traditional methods.

bioRxiv · Oct 19, 2023 · PreprintBioengineering

Selection of HIV-1 for Resistance to Fifth Generation Protease Inhibitors Reveals Two Independent Pathways to High-Level Resistance

E. Spielvogel, S.-K. Lee, S. Zhou, G. J. Lockbaum, M. Henes, A. Sondgeroth, K. Kosovrasti, E. Nalivaika, A. Ali, N. K. Yilmaz, C. A. Schiffer, R. Swanstrom

This study identifies two independent resistance pathways to fifth-generation protease inhibitors in HIV-1 by analyzing mutations under high drug concentrations.

bioRxiv · Jun 23, 2022Microbiology

HIV-1 Protease Uses Bi-Specific S2/S2’ Subsites To Optimize Cleavage of Two Classes of Target Sites

M. Potempa, S.-K. Lee, N. KurtYilmaz, E. A. Nalivaika, A. Rogers, E. Spielvogel, C. W. Carter, C. A. Schiffer, R. Swanstrom

This study shows HIV-1 protease uses bi-specific S2/S2’ subsites to cleave two classes of target sites, with distinct interactions based on the presence or absence of a P1 proline.

bioRxiv · Aug 29, 2018Biochemistry