Author

S.-Q. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Tang· 2 shared J.-H. Wang· 2 shared M.-Q. Dong· 2 shared X. Dong· 2 shared X. Lei· 2 shared Y.-L. Tang· 2 shared Z. Gong· 2 shared B.-H. Li· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

C. Tang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Preferential cross-linking of the stereospecific complex over the encounter complexes by DOPA2, a faster cross-linker than DSS

J.-H. Wang, Z. Gong, X. Dong, S.-Q. Liu, Y.-L. Tang, X. Lei, C. Tang, M.-Q. Dong

This study compares DOPA2 and DSS cross-linkers, finding that faster cross-linking favors the stereospecific complex over encounter complexes in transient protein interactions.

bioRxiv · Jun 6, 2022 · PreprintBiochemistry

Mechanistic origin of different binding affinities of SARS-CoV and SARS-CoV-2 spike RBDs to human ACE2

Z.-B. Zhang, Y.-L. Xia, J.-X. Shen, W.-W. Du, Y.-X. Fu, S.-Q. Liu

This study identifies the molecular mechanisms behind the higher ACE2 binding affinity of SARS-CoV-2 RBD compared to SARS-CoV RBD using computational methods.

bioRxiv · Feb 5, 2022Biophysics

New exon ignites accelerated evolution of placental gene Nrk in the ancestral lineage of eutherians

G. Liu, C. Zhang, Y. Wang, G. Dai, S.-Q. Liu, W. Wang, Y.-H. Pan, J. Ding, H. Li

The paper identifies accelerated evolution in the Nrk gene's exons in eutherian mammals, suggesting a new exon ignited positive selection linked to placental development.

bioRxiv · Feb 9, 2021Evolutionary Biology

A Fast Lysine Cross-linker DOPA Enables Mass Spectrometry Analyses of Protein Unfolding and Weak Protein-protein Interactions

J.-H. Wang, Y.-L. Tang, R. Jain, F. Xiao, Z. Gong, Y. Zhou, D. Tan, Q. Li, X. Dong, S.-Q. Liu, C. Tang, N. Huang, K. Ye, M.-Q. Dong, X. Lei

This study introduces a fast lysine cross-linker DOPA for mass spectrometry analyses, showing it enables rapid protein cross-linking and captures dynamic conformational changes and weak protein-protein interactions.

bioRxiv · Nov 5, 2020 · PreprintBiochemistry

Characterization of dynamic age-dependent changes and driver microbes in primate gut microbiota during host's development and healthy aging via captive crab-eating macaque model

Z.-Y. Wei, J.-H. Rao, M.-T. Tang, G.-A. Zhao, Q.-C. Li, L.-M. Wu, S.-Q. Liu, B.-H. Li, B.-Q. Xiao, X.-Y. Liu, J.-H. Chen

This study characterizes age-dependent changes in primate gut microbiota using crab-eating macaques, identifying key driver microbes and their role in host development and aging.

bioRxiv · Mar 30, 2020 · PreprintMicrobiology