Author

Sarah Macfarlane

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexandrine CarminatiiD· 1 shared Amy L. BowesiD· 1 shared Benjamin ShumiD· 1 shared Erik A. SahaiiD· 1 shared Giovanni GiangrecoiD· 1 shared Karin SchlegelmilchiD· 1 shared Samra TurajliciD· 1 shared Sasha Bailey· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandrine CarminatiORCID

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1 paper

Recent·Most cited

Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma

Karin Schlegelmilch, Viola Hollek, Steven Hooper, Giovanni Giangreco, Sasha Bailey, Sarah Macfarlane, Alexandrine Carminati, Amy L. Bowes, Stephanie Strohbuecker, Benjamin Shum, Samra Turajlic, Xiao Fu, Erik A. Sahai

This study shows that cooperative and antagonistic interactions between sub-clones in melanoma allow multiple resistance mechanisms to coexist, and identifies GSK-J4 as a potential therapeutic target.

bioRxiv · Oct 23, 2025 · PreprintCancer Biology