Author

Viola Hollek

Charité – Universitätsmedizin BerlinORCID 0000-0001-9768-5568Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexandra TrinksiD· 1 shared Alexandrine CarminatiiD· 1 shared Amy L. BowesiD· 1 shared Benjamin ShumiD· 1 shared Bertram KlingeriD· 1 shared Bjoern PapkeiD· 1 shared Channing J. DeriD· 1 shared Christine SersiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alexandra TrinksORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 23, 2025

Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma

Karin Schlegelmilch, Viola Hollek, Steven Hooper…·Erik A. Sahai

This study shows that cooperative and antagonistic interactions between sub-clones in melanoma allow multiple resistance mechanisms to coexist, and identifies GSK-J4 as a potential therapeutic target.

DOI 10.1101/2025.10.23.684170

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologyScience SignalingPeer-reviewedJul 22, 2025

Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer

Oleksandra Aust, Moritz R. T. Thiel, Eric Blanc…·Markus Morkel

5 citations

humanproteomics

𝕏 PostBluesky