Exploration of individual beta cell function over time in vivo: effects of hyperglycemia and glucagon-like peptide-1 receptor (GLP1R) agonism
Luis Fernando Delgadillo-Silva, Shadai Salazar, Livia López–Noriega, AUDREY PROVENCHER-GIRARD, Sandra Larouche, Alexandre Prat, Guy A. Rutter
This study monitors beta cell function in vivo over time, showing hyperglycemia disrupts Ca2+ dynamics and hub cells, while GLP1R agonism restores them.
bioRxiv · Mar 31, 2025 · PreprintPhysiology