Author

Livia López–Noriega

Hammersmith HospitalORCID 0000-0002-2905-9490Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:imaging· 1

Frequent Co-Authors

Guy A. RutteriD· 2 shared Alejandra TomásiD· 1 shared Alexandre PratiD· 1 shared Amelia K. LinnemanniD· 1 shared Asger WretlindiD· 1 shared AUDREY PROVENCHER-GIRARD· 1 shared Ben J. JonesiD· 1 shared Céline Cruciani‐GuglielmacciiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

Guy A. RutterORCID

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2 papers

Recent·Most cited

Exploration of individual beta cell function over time in vivo: effects of hyperglycemia and glucagon-like peptide-1 receptor (GLP1R) agonism

Luis Fernando Delgadillo-Silva, Shadai Salazar, Livia López–Noriega, AUDREY PROVENCHER-GIRARD, Sandra Larouche, Alexandre Prat, Guy A. Rutter

This study monitors beta cell function in vivo over time, showing hyperglycemia disrupts Ca2+ dynamics and hub cells, while GLP1R agonism restores them.

bioRxiv · Mar 31, 2025 · PreprintPhysiology

Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion

Eleni Georgiadou, Charanya Muralidharan, Michelle M. Martinez Irizarry, PAULINE L. CHABOSSEAU, Elina Akalestou, Alejandra Tomás, Fiona Yong Su Wern, Theodoros Stylianides, Asger Wretlind, Cristina Legido‐Quigley, Ben J. Jones, Livia López–Noriega, Yanwen Xu, Guoqiang Gu, Nour Alsabeeh, , Guy A. Rutter

This paper shows that deleting Mfn1 and Mfn2 in beta cells impairs mitochondrial structure and insulin secretion, but incretins can partially compensate through EPAC2 signaling.

Diabetes · Apr 26, 2022Peer-reviewedMolecular Biology