Author

Shane Vedova

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alberto HerreraiD· 1 shared Alexander MarsoniD· 1 shared Alexis TalbotiD· 1 shared Ali DaneshiD· 1 shared Alvin S. HaiD· 1 shared Ana Rafaela TeixeiraiD· 1 shared Brian Rudolph ShyiD· 1 shared Cíntia BittariD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Alberto HerreraORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dynamic Antigen Expression and Intrinsic CTL Resistance in HIV Reservoir Clones

Isabella A. T. M. Ferreira, Alberto Herrera, Tan Thinh Huynh, Nathan L. Board, Emily Stone, Noemi Linden, Yanqin Ren, Cíntia Bittar, Virender Kumar Pal, Shane Vedova, Ethan Naing, Parul Sinha, Ali Danesh, Cristian Ovies, Fitty L Liu, , Richard Brad Jones

This study characterizes HIV reservoir clones and shows they can be culled by sustained CTL pressure, with some displaying intrinsic resistance linked to low oxidative stress.

bioRxiv · Feb 23, 2026 · PreprintImmunology

Hybrid ssDNA repair templates enable high yield genome engineering in primary cells for disease modeling and cell therapy manufacturing

Brian Rudolph Shy, Vivasvan S. Vykunta, Alvin S. Ha, Theodore L. Roth, Alexis Talbot, David N. Nguyen, Yan Yi Chen, Franziska Blaeschke, Shane Vedova, Murad R. Mamedov, Jing-Yi Chung, Hong Li, Jeffrey Lee Wolf, Thomas G Martin, Lumeng Ye, , Alexander Marson

The paper develops a non-viral method using hybrid ssDNA repair templates to improve genome engineering in primary human cells, achieving high knock-in efficiency and cell yields for disease modeling and cell therapy.

bioRxiv · Sep 2, 2021 · PreprintSynthetic Biology