Compensatory Plasticity Defines a Vulnerable Neuronal State in Alzheimers Disease with Psychosis
Matheus B. Victor, Na Sun, Kyriaki Galani, Noelle Leary, Yosuke Tanigawa, Aine Ni Scannail, Li‐Lun Ho, Shaniah Prosper, Liwang Liu, Julia Kofler, Robert A. Sweet, Li‐Huei Tsai, M Kellis
The paper identifies transcriptional changes in upper-layer cortical pyramidal neurons in Alzheimer's disease with psychosis, linking them to network dysfunction and vulnerability.
bioRxiv · Apr 30, 2025 · PreprintNeuroscience