Author
Massachusetts Institute of TechnologyORCID 0000-0003-4364-4028Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Matheus B. Victor, Na Sun, Kyriaki Galani…·M Kellis
The paper identifies transcriptional changes in upper-layer cortical pyramidal neurons in Alzheimer's disease with psychosis, linking them to network dysfunction and vulnerability.
Cinzia Vicidomini, Travis D. Goode, Kathleen M. McAvoy…·Amar Sahay
This study identifies Pla2g2f as a neuroprotective factor that maintains lipid homeostasis and mitigates aging-associated cognitive decline in a mouse model of Alzheimer's disease.
Gwyneth Welch, Carles A. Boix, Eloi Schmauch…·Li‐Huei Tsai
The paper identifies that DNA double strand breaks in neurons activate immune pathways, leading to microglia activation in neurodegeneration.
Matheus B. Victor, Noelle Leary, Xochitl Luna…·Li‐Huei Tsai
This study shows that APOE4 in microglia causes lipid accumulation, impairing their ability to monitor neuronal activity and leading to disrupted neuronal network function.