Shixian Hu

Expanded gut microbial genomes from Chinese populations reveal population-specific genomic features related to human physiological traits

The paper constructs a comprehensive gut microbiome reference database from Chinese and non-Chinese populations, revealing population-specific microbial features linked to host physiology.

The genetic diversity and populational specificity of the human gut virome at single nucleotide resolution

The paper characterizes the human gut virome at single nucleotide resolution using a large Chinese dataset, revealing population-specific genetic variations and their associations with health traits.

Food pairing independently associated with cardiometabolic traits beyond dietary patterns across western and eastern populations

This study identifies food pairing patterns linked to cardiometabolic traits across populations, showing their independent association beyond single-food effects and dietary indices.

Fundamental transport mechanism of mucin-2 ER-to-Golgi trafficking identifies source of ER stress in inflammatory bowel disease

The paper identifies that impaired COPII vesicle enlargement due to reduced TANGO1 expression contributes to ER stress in IBD by affecting mucin-2 secretion.

Effect of host genetics on the gut microbiome in 7,738 participants of the Dutch Microbiome Project

The paper identifies host genetic loci associated with gut microbiome composition and function in a large cohort, finding significant associations near LCT and ABO genes.