Author

Shoko Takehara

Chromosome Engineering Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Anna J. MoyeriD· 2 shared Kanako KazukiiD· 2 shared Mitsuo Oshimura· 2 shared Nandini SinghiD· 2 shared Naohiro NodaiD· 2 shared Naoyo Kajitani· 2 shared Roger H. ReevesiD· 2 shared Satoko MatsukuraiD· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Anna J. MoyerORCID

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2 papers

Recent·Most cited

The first transchromosomic rat model with human chromosome 21 shows robust Down syndrome features

Yasuhiro Kazuki, Feng Gao, Miho Yoshida Yamakawa, Masumi Hirabayashi, Kanako Kazuki, Naoyo Kajitani, Sachiko Miyagawa‐Tomita, Satoshi Abe, Makoto Sanbo, Hiromasa Hara, Hiroshi Kuniishi, Satoshi Ichisaka, Yoshio Hata, Moeka Koshima, Haruka Takayama, , Roger H. Reeves

The paper develops a transchromosomic rat model with human chromosome 21 that exhibits key Down syndrome features and provides a tool for DS research and drug development.

bioRxiv · Oct 3, 2021 · PreprintGenetics

A non-mosaic humanized mouse model of Down syndrome, trisomy of the long arm of human chromosome 21 in mouse chromosome background

Yasuhiro Kazuki, Feng J. Gao, Yicong Li, Anna J. Moyer, Benjamin Devenney, Kei Hiramatsu, Sachiko Miyagawa-Tomita, Satoshi Abe, Kanako Kazuki, Naoyo Kajitani, Narumi Uno, Shoko Takehara, Masato Takiguchi, Miho Yamakawa, Atsushi Hasegawa, , Roger H. Reeves

This paper describes a new non-mosaic humanized mouse model of Down syndrome with a nearly complete copy of the long arm of human chromosome 21.

bioRxiv · Dec 10, 2019 · PreprintGenetics