Author

Silke Förste

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

Martin FischeriD· 2 shared Steve HoffmanniD· 2 shared Alessandro CellerinoiD· 1 shared Alexander V. CherkasoviD· 1 shared Amalie Bech Poulsen· 1 shared Arne SahmiD· 1 shared Bjoern Braendl· 1 shared Danila VoronoviD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Martin FischerORCID

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2 papers

Recent·Most cited

The Greenland shark (Somniosus microcephalus) genome provides insights into extremelongevity

Arne Sahm, Alexander V. Cherkasov, Hequn Liu, Danila Voronov, Kanstantsin Siniuk, Robert J. Schwarz, Oliver Ohlenschlaeger, Silke Förste, Martin Bens, Marco Groth, Ivonne Görlich, Sonia Paturej, Sven Klages, Bjoern Braendl, Jesper Olsen, , Steve Hoffmann

The paper presents a chromosome-level genome assembly of the Greenland shark and identifies genomic features associated with its extreme longevity.

bioRxiv · Sep 9, 2024 · PreprintGenomics

Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress

Luis Coronel, Konstantin Riege, Katjana Schwab, Silke Förste, David Häckes, Lena Semerau, Stephan H. Bernhart, Reiner Siebert, Steve Hoffmann, Martin Fischer

This study identifies RFX7 as a p53-regulated tumor suppressor that activates key genes involved in cell differentiation and apoptosis in response to stress.

Nucleic Acids Research · Jun 22, 2021Peer-reviewedGenomics