Author

Siwei Zhang

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alec R. ChapmaniD· 1 shared Ayjan Semayel· 1 shared Bin MaiD· 1 shared Chang LiuiD· 1 shared David F. LeeiD· 1 shared De-Chang Yang· 1 shared Dong XingiD· 1 shared Fan ZhouiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alec R. ChapmanORCID

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Author profile →

2 papers

Recent·Most cited

AlaRS-mediated lactylation shields PARP1 from ubiquitination to promote HNSCC progression

Jingjing Zhang, Xinru Meng, Qianni Qin, Qikai Zhou, Ying Lu, Runping Qin, Yujuan Yan, Chang Liu, Siwei Zhang, Xiaoyun Luo, Gen Liu, Yingjie Bian, Zhong‐Wei Zhou, Ji‐Chang Zhou, Jinjun Gao, , Litao Sun

This paper identifies AlaRS as a lactyltransferase that lactylates PARP1, preventing its ubiquitination and promoting HNSCC progression, with a potential therapeutic inhibitor identified.

bioRxiv · May 18, 2026 · PreprintMolecular Biology

Genomic Architecture of Cells in Tissues (GeACT): Study of Human Mid-gestation Fetus

Feng Tian, Fan Zhou, Xiang Li, Wenping Ma, Honggui Wu, Ming Yang, Alec R. Chapman, David F. Lee, Longzhi Tan, Dong Xing, Guangjun Yin, Ayjan Semayel, Jing Wang, Jia Wang, Wenjie Sun, , Xiaoliang Sunney Xie

The paper introduces GeACT, a genomic database for human mid-gestation fetus cells, linking gene expression to chromatin states and identifying key transcription factors.

bioRxiv · Apr 12, 2020 · PreprintGenomics