Author

Smriti Chadha

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. YiniD· 1 shared Canchai YangiD· 1 shared Craig C. WelboniD· 1 shared Daniel B. VocelleiD· 1 shared Danielle G. MayiD· 1 shared Dohun PyeoniD· 1 shared Emma W. RosenblumiD· 1 shared Evan N. SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

C. YinORCID

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Author profile →

2 papers

Recent·Most cited

The membrane-associated ubiquitin ligase MARCHF8 promotes cancer immune evasion by degrading MHC class I proteins

M. I. Khalil, Jie Wang, Lexi Vu, Canchai Yang, C. Yin, Smriti Chadha, Harrison Nabors, Daniel B. Vocelle, Danielle G. May, Rachel J. Chrisopulos, Craig C. Welbon, Li Zhou, Kyle J. Roux, William Charles Spanos, Matthew P. Bernard, , Dohun Pyeon

This study identifies MARCHF8 as a driver of cancer immune evasion by degrading MHC-I proteins and shows its inhibition enhances antitumor immunity and response to immunotherapy.

Proceedings of the National Academy of Sciences · Mar 9, 2026Peer-reviewedCancer Biology

Tentorium cerebelli notch severity in the human brain: protocol, distribution and histopathology validation

Smriti Chadha, Joshua L. Chase, Emma W. Rosenblum, Evan N. Smith, Nathaniel David Mercaldo, Matthew P. Frosch, Jean C. Augustinack

The paper develops a protocol to assess tentorial notch severity in the entorhinal cortex using postmortem samples and finds a positive correlation between TN severity and penumbra scores.

bioRxiv · Sep 18, 2025 · PreprintNeuroscience