Author

Sophia Schlorf

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Cara L. GreeniD· 3 shared Chung‐Yang YehiD· 3 shared David A. HarrisiD· 3 shared Diana Vertein· 3 shared Dudley W. LammingiD· 3 shared Isaac Grunow· 3 shared Luigi PuglielliiD· 3 shared Michelle M. SonsallaiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

Cara L. GreenORCID

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Author profile →

3 papers

Recent·Most cited

Dietary sugar type determines the response to protein restriction in females, but not males

Michelle M. Sonsalla, Mari Cole, Madeline Johnson, Samuel Cai, Brenna Virnig, Alexandra Trebil, Reji Babygirija, Julia A. Illiano, Diana Vertein, Yang Liu, Isaac Grunow, Bailey A. Knopf, Sophia Schlorf, Michael Rigby, Chung‐Yang Yeh, , Dudley W. Lamming

The paper shows that in female mice, carbohydrate quality affects metabolic and neurological responses to low protein diets, but not in males.

bioRxiv · Aug 23, 2026 · PreprintPhysiology

Restriction of individual branched-chain amino acids has distinct effects on the development and progression of Alzheimers disease in 3xTg mice

Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, C. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, , Dudley W. Lamming

This study examines the effects of restricting individual branched-chain amino acids on Alzheimer's disease progression in 3xTg mice, finding sex-specific cognitive and metabolic benefits.

Advanced Science · Mar 12, 2026Peer-reviewedPhysiology

Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer&aposs disease

Reji Babygirija, Jessica H. Han, Michelle M. Sonsalla, Ryan Matoska, Mariah F. Calubag, Cara L. Green, Anna Tobon, Chung‐Yang Yeh, Diana Vertein, Sophia Schlorf, Julia Illiano, Yang Liu, Isaac Grunow, Michael J. Rigby, Luigi Puglielli, , Dudley W. Lamming

This study shows that fasting, not just calorie reduction, is necessary for many benefits of caloric restriction in 3xTg mice with Alzheimer's disease.

Nature Communications · Aug 4, 2025Peer-reviewedPhysiology