Author

Sophie Lebon

Primary ORCID profile (0000-0003-0039-5519 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Sophie LeboniD2 papers · Centre National de la Recherche Scientifique

Biology Disciplines

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A David Edwards· 1 shared Alka SaxenaiD· 1 shared Amélie Montané· 1 shared Andrée Delahaye-Duriez· 1 shared Anne-Laure SchangiD· 1 shared Bobbi FleissiD· 1 shared Cindy BokobzaiD· 1 shared Claire Leconte· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A David Edwards

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1 paper

Recent·Most cited

Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury

Juliette Van Steenwinckel, Anne-Laure Schang, Michelle L Krishnan, Vincent Degos, Andrée Delahaye-Duriez, Cindy Bokobza, Franck Verdonk, Amélie Montané, Stéphanie Sigaut, Olivier Hennebert, Sophie Lebon, Leslie Schwendimann, Tifenn Le Charpentier, Rahma Hassan-Abdi, Gareth Ball, , Pierre Gressens

The paper shows that reduced Wnt/β-catenin signaling in microglia of the developing brain causes pro-inflammatory activation and white matter injury, and that restoring this pathway can prevent these effects.

bioRxiv · May 31, 2018 · PreprintImmunology