Stefan Eimer

Shroom3-dependent pillar cell constriction establishes a mechanical threshold for respiratory lamellar stability

This study identifies Shroom3 and Vinculin b as regulators of contractile apparatuses in zebrafish pillar cells, showing their role in maintaining lamellar stability under mechanical stress.

Patterned integrin-laminin adhesion coordinates epithelial collective cell migration

The paper shows integrins 3 and 6, along with laminin 5, coordinate epithelial collective migration in zebrafish pLLP by maintaining basement membrane integrity and regulating protrusive activity.

Flower/1 FLWR-1 regulates neuronal activity via the plasma membrane Ca2+-ATPase to promote recycling of synaptic vesicles

This study investigates the role of FLWR-1 in synaptic vesicle recycling and neuronal activity in C. elegans, finding it regulates Ca2+ levels via PMCA and affects excitation-inhibition balance.

Phosphoribosyl ubiquitination of SNARE proteins regulate autophagy in Legionella infection

This study identifies that phosphoribosyl ubiquitination of SNARE proteins STX17 and SNAP29 by Legionella SidE effectors regulates autophagy hijacking during infection.

Disruption of the MICOS complex leads to an aberrant cristae structure and an unexpected, pronounced lifespan extension in Podospora anserina

This study shows that disrupting the MICOS complex in Podospora anserina leads to altered mitochondrial structure and extended lifespan, with different subcomplexes affecting lifespan through distinct mechanisms.

RAB18 impacts autophagy via lipid droplet-derived lipid transfer and is rescued by ATG9A

This study shows RAB18 regulates autophagy by linking lipid droplets to lipid supply, and ATG9A phosphorylation can partially restore autophagy when RAB18 is absent.